Indications for: TEZSPIRE
Add-on maintenance treatment of severe asthma.
Limitations of Use:
Not for relief of acute bronchospasm or status asthmaticus.
Give by SC inj into upper arm, thigh, or abdomen (except around the navel). Rotate inj sites. 210mg once every 4 weeks.
<12yrs: not established.
Not for treating acute asthma symptoms or exacerbations. Avoid abrupt discontinuation of any corticosteroids upon Tezspire initiation; reduce gradually if appropriate. Treat pre-existing helminth infections prior to initiation; if infection develops and unresponsive to antihelmintics, discontinue Tezspire until resolves. Do not inject into tender, bruised, erythematous, or hardened skin. Pregnancy (during 3rd trimester). Nursing mothers.
Thymic stromal lymphopoietin (TSLP) blocker.
Avoid concomitant live attenuated vaccines.
Pharyngitis, arthralgia, back pain; hypersensitivity reactions (eg, rash, allergic conjunctivitis).
Generic Drug Availability:
Single-dose vial or prefilled syringe—1