Bone disorders:

Indications for: Teriparatide Injection

Postmenopausal osteoporosis in women who are at high risk for fracture. To increase bone mass in men with primary or hypogonadal osteoporosis who are at high risk for fracture. Treatment of men and women with osteoporosis associated with sustained glucocorticoid therapy at high risk for fracture (see full labeling).

Adult Dosage:

20mcg SC once daily into thigh or abdominal wall; may treat for up to 2 years.

Children Dosage:

Not established.

Boxed Warning:

Potential risk of osteosarcoma.

Teriparatide Injection Warnings/Precautions:

Increased baseline risk for osteosarcoma (eg, Paget's disease of bone, unexplained increased alkaline phosphatase, open epiphyses, prior skeletal radiation therapy), bone metastases, history of skeletal malignancies, metabolic bone disease, hypercalcemia or risk thereof (eg, hyperparathyroidism): not recommended. Urolithiasis. Hypercalciuria. Hepatic, renal, or cardiac disease. Pregnancy. Nursing mothers: not recommended.

Teriparatide Injection Classification:

Hormone (human parathyroid hormone, recombinant).

Teriparatide Injection Interactions:

Caution with digoxin (teriparatide-induced hypercalcemia increases risk of toxicity).

Adverse Reactions:

Arthralgia, pain, nausea; transient orthostatic hypotension, hypercalcemia, hyperuricemia, inj site reactions.

How Supplied:

Single-patient-use pens (2.48mL)—1