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Tarpeyo Generic Name & Formulations
Legal Class
Rx
General Description
Budesonide 4mg; del-rel caps.
Pharmacological Class
Glucocorticoid.
How Supplied
Caps—120
Manufacturer
Generic Availability
NO
Tarpeyo Indications
Indications
To reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgAN) at risk of rapid disease progression, generally a urine protein-to-creatinine ratio (UPCR) ≥1.5 g/g.
Tarpeyo Dosage and Administration
Adult
Swallow whole. Take in the AM at least 1hr before a meal. 16mg once daily. Treat for 9 months. When discontinuing treatment, reduce dose to 8mg once daily for the last 2 weeks.
Children
Not established.
Tarpeyo Contraindications
Not Applicable
Tarpeyo Boxed Warnings
Not Applicable
Tarpeyo Warnings/Precautions
Warnings/Precautions
Avoid in active or quiescent tuberculosis, untreated fungal, bacterial, systemic viral or parasitic infections, or ocular herpes simplex. If exposed to chickenpox or measles, consider immune globulin or antiviral prophylactic therapies. Supplement with systemic corticosteroids in surgery or other stress situations. Monitor for adrenal axis suppression when discontinuing therapy or switching between corticosteroids. Hypertension. Diabetes. Osteoporosis. Peptic ulcer. Glaucoma. Cataracts. Moderate hepatic impairment: monitor for hypercorticism. Severe hepatic impairment: avoid. Elderly. Pregnancy. Nursing mothers.
Tarpeyo Pharmacokinetics
See Literature
Tarpeyo Interactions
Interactions
Avoid grapefruit juice. May be potentiated by potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir, indinavir, saquinavir, erythromycin, cyclosporine); avoid. May decrease immune response to some vaccines.
Tarpeyo Adverse Reactions
Adverse Reactions
Hypertension, peripheral edema, muscle spasms, acne, dermatitis, weight increase, dyspnea, face edema, dyspepsia, fatigue, hirsutism; hypercorticism.
Tarpeyo Clinical Trials
See Literature
Tarpeyo Note
Not Applicable
Tarpeyo Patient Counseling
See Literature
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