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Sutab Generic Name & Formulations
Legal Class
Rx
General Description
Sodium sulfate 1.479g, magnesium sulfate 0.225g, potassium chloride 0.188g; per tab.
Pharmacological Class
Osmotic laxative.
How Supplied
Tabs—24 (w. 16oz container)
Manufacturer
Generic Availability
NO
Sutab Indications
Indications
Bowel cleansing prior to colonoscopy.
Sutab Dosage and Administration
Adult
Split-dose regimen (1st dose start the evening before colonoscopy): 12 tabs with 16oz of water over 15–20mins; approx. 1hr after the last tab is ingested, drink additional 16oz of water over 30mins; then approx. after 30mins, drink another 16oz of water over 30mins; (2nd dose start next morning): repeat on day of colonoscopy 5–8hrs before procedure and no sooner than 4hrs from starting Dose 1. Total regimen: 24 tabs. Complete all tabs and water at least 2hrs before colonoscopy.
Children
Not established.
Sutab Contraindications
Contraindications
GI obstruction or ileus. Bowel perforation. Toxic colitis. Toxic megacolon. Gastric retention.
Sutab Boxed Warnings
Not Applicable
Sutab Warnings/Precautions
Warnings/Precautions
Maintain adequate hydration. Correct fluid and electrolyte abnormalities before therapy. Renal impairment; monitor baseline and post-colonoscopy electrolytes, creatinine, BUN. History of QT prolongation, uncontrolled arrhythmias, recent MI, unstable angina, CHF, or cardiomyopathy: increased risk of arrhythmias; consider ECGs at pre-dose and post-colonoscopy. History of seizures. Hyponatremia. Inflammatory bowel disease. Colonic mucosal ulcerations. Ischemic colitis. Severe ulcerative colitis. Elderly. Pregnancy. Nursing mothers.
Sutab Pharmacokinetics
See Literature
Sutab Interactions
Interactions
Caution with concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal: may increase risk of seizures. Caution with drugs that may increase risk for fluid or electrolyte disturbances, arrhythmias or QT prolongation. Administer oral medications at least 1hr before starting each dose of Sutab. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, and penicillamine at least 2hrs before and not less than 6hrs after Sutab to avoid chelation with magnesium. Avoid concomitant stimulant laxatives (eg, bisacodyl, sodium picosulfate).
Sutab Adverse Reactions
Adverse Reactions
Nausea, abdominal distension, vomiting, upper abdominal pain; electrolyte abnormalities, renal injury.
Sutab Clinical Trials
See Literature
Sutab Note
Not Applicable
Sutab Patient Counseling
See Literature
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