• Constipation and bowel cleansers

Sutab Generic Name & Formulations

General Description

Sodium sulfate 1.479g, magnesium sulfate 0.225g, potassium chloride 0.188g; per tab.

Pharmacological Class

Osmotic laxative.

How Supplied

Tabs—24 (w. 16oz container)

Generic Availability


Sutab Indications


Bowel cleansing prior to colonoscopy.

Sutab Dosage and Administration


Split-dose regimen (1st dose start the evening before colonoscopy): 12 tabs with 16oz of water over 15–20mins; approx. 1hr after the last tab is ingested, drink additional 16oz of water over 30mins; then approx. after 30mins, drink another 16oz of water over 30mins; (2nd dose start next morning): repeat on day of colonoscopy 5–8hrs before procedure and no sooner than 4hrs from starting Dose 1. Total regimen: 24 tabs. Complete all tabs and water at least 2hrs before colonoscopy.


Not established.

Sutab Contraindications


GI obstruction or ileus. Bowel perforation. Toxic colitis. Toxic megacolon. Gastric retention.

Sutab Boxed Warnings

Not Applicable

Sutab Warnings/Precautions


Maintain adequate hydration. Correct fluid and electrolyte abnormalities before therapy. Renal impairment; monitor baseline and post-colonoscopy electrolytes, creatinine, BUN. History of QT prolongation, uncontrolled arrhythmias, recent MI, unstable angina, CHF, or cardiomyopathy: increased risk of arrhythmias; consider ECGs at pre-dose and post-colonoscopy. History of seizures. Hyponatremia. Inflammatory bowel disease. Colonic mucosal ulcerations. Ischemic colitis. Severe ulcerative colitis. Elderly. Pregnancy. Nursing mothers.

Sutab Pharmacokinetics

See Literature

Sutab Interactions


Caution with concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal: may increase risk of seizures. Caution with drugs that may increase risk for fluid or electrolyte disturbances, arrhythmias or QT prolongation. Administer oral medications at least 1hr before starting each dose of Sutab. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, and penicillamine at least 2hrs before and not less than 6hrs after Sutab to avoid chelation with magnesium. Avoid concomitant stimulant laxatives (eg, bisacodyl, sodium picosulfate).

Sutab Adverse Reactions

Adverse Reactions

Nausea, abdominal distension, vomiting, upper abdominal pain; electrolyte abnormalities, renal injury.

Sutab Clinical Trials

See Literature

Sutab Note

Not Applicable

Sutab Patient Counseling

See Literature