Ssd Af

  • Skin infections (topicals)

Ssd Af Generic Name & Formulations

General Description

Silver sulfadiazine 1%; crm; alcohol-free.

Pharmacological Class

Sulfonamide antibacterial.

See Also

How Supplied

SSD—25g, 50g, 85g, 400g
SSD AF—50g, 400g

Ssd Af Indications


Prophylaxis and treatment of sepsis in 2nd and 3rd degree burns.

Ssd Af Dosage and Administration


Apply 1–2 times daily aseptically to approximately 1/16 inch depth to cleansed and debrided burns. Reapply promptly if removed. Continue until wound is healed. May be occluded.


Not recommended.

Ssd Af Contraindications


Premature infants. Within first 2 months of birth. Late pregnancy.

Ssd Af Boxed Warnings

Not Applicable

Ssd Af Warnings/Precautions


G6PD deficiency. Impaired renal or hepatic function. Monitor serum sulfa levels and renal function in extensive burns. Pregnancy (Cat.B). Nursing mothers: not recommended.

Ssd Af Pharmacokinetics

See Literature

Ssd Af Interactions


Leukopenia increased with concomitant cimetidine. May inactivate debriding enzymes.

Ssd Af Adverse Reactions

Adverse Reactions

Transient leukopenia, skin necrosis, erythema multiforme, skin discoloration, burning sensation, rash, fungal overgrowth, interstitial nephritis, systemic sulfonamide reactions.

Ssd Af Clinical Trials

See Literature

Ssd Af Note

Not Applicable

Ssd Af Patient Counseling

See Literature