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Slynd Generic Name & Formulations
Legal Class
Rx
General Description
Drospirenone 4mg (24 tabs); inert (4 tabs).
Pharmacological Class
Progestin.
How Supplied
Packs—1, 3, 6
Manufacturer
Generic Availability
NO
Slynd Indications
Indications
Oral contraception.
Slynd Dosage and Administration
Adult
Swallow whole. 1 tab daily for 28 days; repeat.
Children
Pre-menarche: not applicable.
Slynd Contraindications
Contraindications
Renal impairment. Adrenal insufficiency. Presence or history of progestin sensitive cancers. Liver tumors (benign or malignant). Hepatic impairment. Undiagnosed abnormal uterine bleeding.
Slynd Boxed Warnings
Not Applicable
Slynd Warnings/Precautions
Warnings/Precautions
Hyperkalemia or risk thereof. History of thromboembolism. Discontinue if thromboembolic event, jaundice, or liver dysfunction occurs. Consider discontinuing if prolonged immobilization due to surgery or illness. Bone loss. Diabetes. Evaluate for other causes if irregular uterine bleeding or amenorrhea persists. History of depression; monitor and discontinue if serious depression recurs. Postpartum period. Pregnancy: discontinue if occurs.
Slynd Pharmacokinetics
See Literature
Slynd Interactions
Interactions
Monitor serum K+ during 1st cycle with drugs that increase potassium (eg, ACE inhibitors, ARBs, NSAIDs, K+-sparing diuretics, K+-supplements, heparin, aldosterone antagonists); consider monitoring in high-risk patients taking concomitant long-term strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, voriconazole, indinavir, boceprevir, clarithromycin). May be antagonized by CYP3A4 or other enzyme inducers (eg, aprepitant, barbiturates, bosentan, carbamazepine, efavirenz, felbamate, griseofulvin, oxcarbazepine, phenytoin, rifampin, rifabutin, rufinamide, St. John's wort); use backup or alternative method of contraception.
Slynd Adverse Reactions
Adverse Reactions
Acne, metrorrhagia, headache, breast pain, weight increased, dysmenorrhea, nausea, vaginal hemorrhage, libido decreased, breast tenderness, menstruation irregular; serious thromboembolic events, ectopic pregnancy.
Slynd Clinical Trials
See Literature
Slynd Note
Not Applicable
Slynd Patient Counseling
See Literature
