• Contraception

Slynd Generic Name & Formulations

General Description

Drospirenone 4mg (24 tabs); inert (4 tabs).

Pharmacological Class


How Supplied

Packs—1, 3, 6


Generic Availability


Slynd Indications


Oral contraception.

Slynd Dosage and Administration


Swallow whole. 1 tab daily for 28 days; repeat.


Pre-menarche: not applicable.

Slynd Contraindications


Renal impairment. Adrenal insufficiency. Presence or history of progestin sensitive cancers. Liver tumors (benign or malignant). Hepatic impairment. Undiagnosed abnormal uterine bleeding.

Slynd Boxed Warnings

Not Applicable

Slynd Warnings/Precautions


Hyperkalemia or risk thereof. History of thromboembolism. Discontinue if thromboembolic event, jaundice, or liver dysfunction occurs. Consider discontinuing if prolonged immobilization due to surgery or illness. Bone loss. Diabetes. Evaluate for other causes if irregular uterine bleeding or amenorrhea persists. History of depression; monitor and discontinue if serious depression recurs. Postpartum period. Pregnancy: discontinue if occurs.

Slynd Pharmacokinetics

See Literature

Slynd Interactions


Monitor serum K+ during 1st cycle with drugs that increase potassium (eg, ACE inhibitors, ARBs, NSAIDs, K+-sparing diuretics, K+-supplements, heparin, aldosterone antagonists); consider monitoring in high-risk patients taking concomitant long-term strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, voriconazole, indinavir, boceprevir, clarithromycin). May be antagonized by CYP3A4 or other enzyme inducers (eg, aprepitant, barbiturates, bosentan, carbamazepine, efavirenz, felbamate, griseofulvin, oxcarbazepine, phenytoin, rifampin, rifabutin, rufinamide, St. John's wort); use backup or alternative method of contraception.

Slynd Adverse Reactions

Adverse Reactions

Acne, metrorrhagia, headache, breast pain, weight increased, dysmenorrhea, nausea, vaginal hemorrhage, libido decreased, breast tenderness, menstruation irregular; serious thromboembolic events, ectopic pregnancy.

Slynd Clinical Trials

See Literature

Slynd Note

Not Applicable

Slynd Patient Counseling

See Literature