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Skelaxin Generic Name & Formulations
Legal Class
Rx
General Description
Metaxalone 800mg; scored tabs.
Pharmacological Class
Muscle relaxant (central).
How Supplied
Tabs—100, 500
Manufacturer
Generic Availability
YES
Skelaxin Indications
Indications
As adjunct treatment for acute, painful musculoskeletal conditions.
Skelaxin Dosage and Administration
Adult
800mg 3–4 times daily.
Children
≤12yrs: not established.
Skelaxin Contraindications
Contraindications
Anemias. Significant renal or hepatic dysfunction.
Skelaxin Boxed Warnings
Not Applicable
Skelaxin Warnings/Precautions
Warnings/Precautions
Renal or hepatic impairment (monitor LFTs). Elderly. Pregnancy, nursing mothers: not recommended.
Skelaxin Pharmacokinetics
See Literature
Skelaxin Interactions
Interactions
Increased risk of sedation, respiratory depression with concomitant other CNS depressants (eg, alcohol, benzodiazepines, opioids, TCAs); monitor closely. Risk of serotonin syndrome with serotonergic drugs (eg, SSRIs, SNRIs, TCAs, triptans, 5-HT3 antagonists, opioids, mirtazapine, trazodone, tramadol, MAOIs, linezolid, IV methylene blue); monitor and discontinue if suspected. Concomitant with food may enhance CNS depression. May cause false (+) Benedict's test.
Skelaxin Adverse Reactions
Adverse Reactions
Drowsiness, dizziness, headache, nervousness, GI upset, rash, jaundice, hemolytic anemia, leukopenia; hypersensitivity reactions.
Skelaxin Clinical Trials
See Literature
Skelaxin Note
Not Applicable
Skelaxin Patient Counseling
See Literature
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