Salsalate Generic Name & Formulations
Salsalate 500mg, 750mg; scored tabs.
Rheumatoid arthritis. Osteoarthritis.
Salsalate Dosage and Administration
3g daily in divided doses.
Varicella or influenza in teenagers. 3rd trimester pregnancy. Aspirin allergy. Coronary artery bypass graft surgery.
Salsalate Boxed Warnings
Advanced renal disease: not recommended. Impaired renal or hepatic function. Hypertension. Heart failure. Edema. Bleeding disorders. Monitor blood, liver, renal function with chronic use. Peptic ulcer. Gastritis. Diabetes. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.
PABA may increase serum levels. May potentiate anticoagulants, hypoglycemics, methotrexate. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize uricosurics and spironolactone.
Salsalate Adverse Reactions
Salicylism, tinnitus, nausea, dyspepsia, GI bleed, hearing loss, rash (discontinue if occurs). See literature re: risk of cardiovascular events.
Salsalate Clinical Trials
Formerly known under the brand names Disalcid, Salflex.
Salsalate Patient Counseling