• Hyperacidity, GERD, and ulcers

Robinul Generic Name & Formulations

General Description

Glycopyrrolate 1mg; dye-free tabs.

Pharmacological Class


See Also

How Supplied

Tabs—30, 90


Generic Availability


Robinul Indications


Adjunct in peptic ulcer.

Limitations of Use

Not indicated as monotherapy for treatment of peptic ulcer because effectiveness in peptic ulcer healing has not been established.

Robinul Dosage and Administration


Use lowest effective dose. Initially 1mg 3 times daily, may need 2mg at bedtime to assure overnight control; max 8mg daily. Maintenance: 1mg 2 times daily.


Not established.

Robinul Contraindications


Glaucoma. Obstructive uropathies, including prostatic hypertrophy. Mechanical obstructive diseases of the GI tract (eg, pyloroduodenal stenosis, strictures). GI motility disorders (eg, achalasia, paralytic ileus, intestinal atony). Bleeding GI ulcer. Active inflammatory or infectious colitis. Toxic megacolon. Myasthenia gravis.

Robinul Boxed Warnings

Not Applicable

Robinul Warnings/Precautions


Precipitation of acute glaucoma. IOP. Partial or complete mechanical intestinal obstruction. Ileostomy. Colostomy. Monitor for decreased GI motility. Cognitive or visual impairment. Conditions exacerbated by anticholinergic effects (eg, autonomic neuropathy, hyperthyroidism, cardiac disease, hiatal hernia due to reflux esophagitis). Avoid exposure to hot or very warm environmental temperatures. Renal impairment: monitor. Increased risk of anticholinergic adverse reactions in elderly (≥65yrs): not recommended. Pregnancy. Nursing mothers.

Robinul Pharmacokinetics

See Literature

Robinul Interactions


Additive anticholinergic effects with other anticholinergics (eg, tricyclics, antiepileptics, class I antiarrhythmics, antispasmodics, amantadine) or other medications that decrease GI motility: not recommended. Concomitant use with solid oral dosage forms of potassium chloride may worsen GI mucosal injury due to decreased gastric motility and increased transit time: not recommended.

Robinul Adverse Reactions

Adverse Reactions

Blurred vision, drowsiness, decreased sweating, flushing, vomiting, constipation, dry mouth, tachycardia, urinary retention.

Robinul Clinical Trials

See Literature

Robinul Note

Not Applicable

Robinul Patient Counseling

See Literature