Anesthetics:

Indications for REGONOL:

As a reversal agent or antagonist to the neuromuscular blocking effects of nondepolarizing muscle relaxants.

Adult Dosage:

Individualize. Give by IV inj. Usual range: 0.1–0.25mg/kg. Give atropine sulfate or equipotent dose of glycopyrrolate immediately prior to or simultaneously with Regonol.

Children Dosage:

Not recommended.

REGONOL Contraindications:

Intestinal or urinary obstruction.

REGONOL Warnings/Precautions:

Bronchial asthma. Cardiac dysrhythmias. Electrolyte imbalance. Adrenal cortical insufficiency. Renal impairment. Neonates. Pregnancy (Cat.C).

REGONOL Classification:

Cholinesterase inhibitor.

REGONOL Interactions:

Concomitant 4-aminopyridine may delay onset. Possible resistance to reversal with antibiotics associated with paralysis (eg, aminoglycosides, tetracyclines, bacitracin, polymyxin B, colistin, sodium colistimethate). Recurrent paralysis possible with quinidine. Magnesium salts may enhance neuromuscular blockade and interfere with restoration.

Adverse Reactions:

GI upset, increased salivation and bronchial secretions, miosis and diaphoresis, muscle cramps, fasciculation and weakness, rash.

How Supplied:

Ampules (2mL)—10