Recombivax Hb Dialysis Generic Name & Formulations
Legal Class
Rx
General Description
Hepatitis B surface antigen vaccine (recombinant) 40mcg/mL; susp for IM inj; aluminum hydroxide adsorbed; preservative-free.
Pharmacological Class
HB.
How Supplied
Single-dose vials: Ped/Adolescent 5mcg/0.5mL (yellow cap)—1, 10; Adult 10mcg/1mL (green cap)—1, 10; Dialysis 40mcg/1mL (blue cap)—1
Manufacturer
Recombivax Hb Dialysis Indications
Indications
Hepatitis B immunization.
Recombivax Hb Dialysis Dosage and Administration
Adults and Children
Use correct formulation; see literature. Give IM into anterolateral thigh for children; deltoid for adults. May give SC if risk of hemorrhage. Patients 0–19yrs of age (three-dose regimen): give 1st dose of 5mcg at elected date and repeat after 1 month (2nd dose) and 6 months after first dose (3rd dose). Or, for patients 11–15yrs of age, may use alternate two-dose regimen: give 1st dose of 10mcg at elected date and repeat after 4–6 months (2nd dose). Patients ≥20yrs of age: give 1st dose of 10mcg at elected date and repeat after 1 month (2nd dose) and 6 months after first dose (3rd dose). Dialysis and pre-dialysis patients: give 1st dose of 40mcg at elected date and repeat after 1 month (2nd dose) and 6 months after first dose (3rd dose); consider booster dose if antibody levels fall to <10mIU/mL. High-risk infants (mother is HBsAg positive or unknown) or if exposed to HBsAg: give hepatitis B immune globulin also (see literature).
Recombivax Hb Dialysis Contraindications
Contraindications
Yeast hypersensitivity.
Recombivax Hb Dialysis Boxed Warnings
Not Applicable
Recombivax Hb Dialysis Warnings/Precautions
Warnings/Precautions
Have epinephrine inj (1:1000) available. Serious active infection. Severely compromised cardiopulmonary status. Pregnancy (Cat.C). Nursing mothers.
Recombivax Hb Dialysis Pharmacokinetics
See Literature
Recombivax Hb Dialysis Interactions
Recombivax Hb Dialysis Adverse Reactions
Adverse Reactions
Local reactions, irritability, fatigue, headache, fever, malaise, nausea, diarrhea, anorexia, pharyngitis, upper respiratory infection, anaphylaxis.
Recombivax Hb Dialysis Clinical Trials
See Literature
Recombivax Hb Dialysis Note
Not Applicable
Recombivax Hb Dialysis Patient Counseling
See Literature