Miscellaneous neurodegenerative disorders:

Indications for RADICAVA:

Amyotrophic lateral sclerosis (ALS).


Give as IV infusion over 60mins. Initial cycle: 60mg (given as two consecutive 30mg infusions) daily for 14 days, followed by 14 days off. Subsequent cycles: 60mg daily for 10 days out of 14-day periods, followed by 14 days off.


Not established.


Monitor for hypersensitivity reactions; discontinue and treat if occur. Asthma. Sulfite sensitivity. Pregnancy. Nursing mothers.

Pharmacologic Class:

Free radical scavenger.

Adverse Reactions:

Confusion, gait disturbance, headache, dermatitis, eczema, respiratory failure/disorders, hypoxia, glycosuria, tinea infection; hypersensitivity reactions, anaphylaxis.

Generic Availability:


How Supplied:

Single-dose bags—1, 2