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Rabavert Generic Name & Formulations
Legal Class
Rx
General Description
Rabies vaccine, inactivated 2.5IU/mL; pwd for IM inj after reconstitution; may contain trace amounts of bovine gelatin, chicken protein, neomycin, chlortetracycline, and amphotericin B.
How Supplied
Single-dose vial—1 (w. diluent)
Manufacturer
Rabavert Indications
Indications
Preexposure immunization and post-exposure prophylaxis of rabies.
Rabavert Dosage and Administration
Adults and Children
Adults: inject into deltoid area. Small children: inject into thigh. Preexposure immunization: 3 inj of 1mL IM each on day 0, 7, and either day 21 or 28. Booster: 1 dose as needed to maintain antibody titer (see literature). Post-exposure prophylaxis: a 5-dose regimen of 1mL IM given on days 0, 3, 7, 14, and 28 (give 1st dose with human rabies immunoglobulin at a separate site). If previously immunized: 2 inj of 1mL each on days 0 and 3 (no immune globulin needed).
Rabavert Contraindications
Not Applicable
Rabavert Boxed Warnings
Not Applicable
Rabavert Warnings/Precautions
Warnings/Precautions
Immunocompromised: may get suboptimal response (monitor titers). Postpone preexposure immunization during acute febrile illness or infection. Egg allergy. Have epinephrine inj (1:1000) available. Pregnancy (Cat.C).
Rabavert Pharmacokinetics
See Literature
Rabavert Interactions
Interactions
Immunosuppressants: may get suboptimal response.
Rabavert Adverse Reactions
Adverse Reactions
Local reactions, lymphadenopathy, headache, myalgia, malaise, dizziness, neuroparalytic events, anaphylaxis.
Rabavert Clinical Trials
See Literature
Rabavert Note
Not Applicable
Rabavert Patient Counseling
See Literature
