Topical pain relief:

Indications for QUTENZA:

Treatment of neuropathic pain associated with post-herpetic neuralgia (PHN) or with diabetic peripheral neuropathy (DPN) of the feet.

Adult Dosage:

Identify treatment area and mark the skin; may cut patches to match size and shape of area. Pretreat with topical anesthetic to reduce discomfort, once anesthetized, remove anesthetic and wash the treatment area. Administer in a well-ventilated area. Apply to dry, intact skin within 2hrs of opening patch. Apply patch (up to 4 may be used) for 60mins (PHN) or 30mins (DPN); may repeat every 3 months or as warranted by the return of pain (not more frequently than every 3 months). May use a dressing to ensure patch remains in contact with treatment area. After removal of patch, apply Cleansing Gel to area and leave on for at least one minute. Remove Cleansing Gel with dry wipe; wash and dry the area. Treat acute pain during and following the procedure with local cooling and/or analgesics. Use nitrile gloves, face mask, and protective glasses when handling patch and cleaning capsaicin residue from skin. Immediately dispose of patches.

Children Dosage:

<18yrs: not established.

QUTENZA Warnings/Precautions:

Should only be administered by a physician or healthcare professional. Severe irritation with unintended exposure (eg, eyes, mucous membranes, respiratory tract, skin). Aerosolization of capsaicin may occur with rapid removal of patches; remove patches slowly by rolling the adhesive side inward. DPN: examine feet for skin lesions related to underlying neuropathy or vascular insufficiency prior to each application. Evaluate for recent history of cardio- and cerebrovascular disease. Monitor BP periodically during treatment. Preexisting sensory deficits: assess for sensory deterioration or loss prior to each application; reconsider treatment if detected or worsens. Pregnancy. Nursing mothers.

QUTENZA Classification:

TRPV1 channel agonist.

Adverse Reactions:

Application site reactions (eg, erythema, pain, pruritus, papules); increased blood pressure.

How Supplied:

Patch—1, 2 (both with 50g tube of Cleansing Gel)