Migraine and headache:

Recent Updates:

Monograph added.

Indications for: QULIPTA

Preventative treatment of episodic migraine.

Adult Dosage:

10mg, 30mg, or 60mg once daily. Concomitant strong CYP3A4 inhibitors: 10mg once daily. Concomitant strong or moderate CYP3A4 inducers: 30mg or 60mg once daily. Concomitant OATP inhibitors: 10mg or 30mg once daily. Severe renal impairment, ESRD: 10mg once daily.

Children Dosage:

Not established.

QULIPTA Warnings/Precautions:

Severe hepatic impairment: avoid. Severe renal impairment (CrCl 15–29mL/min), ESRD (CrCl <15mL/min): adjust dose; see Adult. ESRD on intermittent dialysis: give after session. Elderly. Pregnancy. Nursing mothers.

QULIPTA Classification:

Calcitonin gene-related peptide (CGRP) receptor antagonist.

QULIPTA Interactions:

Potentiated by strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, clarithromycin) or OATP inhibitors (eg, cyclosporine, rifampin); adjust dose with concomitant use; see Adult. Antagonized by strong or moderate CYP3A4 inducers (eg, rifampin, carbamazepine, phenytoin, St. John's wort, efavirenz, etravirine); adjust dose with concomitant use; see Adult.

Adverse Reactions:

Nausea, constipation, fatigue.

Generic Drug Availability:

NO

How Supplied:

Tabs—30

Pricing for QULIPTA

60mg tablet (Qty: 30)
Appx. price $1020
GoodRx