Quillivant Xr Generic Name & Formulations
Legal Class
CII
General Description
Methylphenidate HCl ext-rel 5mg/mL; pwd for oral susp after reconstitution.
Pharmacological Class
CNS stimulant.
How Supplied
Bottles (w. oral dosing dispenser)—60mL, 120mL, 150mL, 180mL
Manufacturer
Generic Availability
NO
Quillivant Xr Indications
Indications
Attention deficit hyperactivity disorder.
Quillivant Xr Dosage and Administration
Adults and Children
<6yrs: not established. ≥6yrs: Individualize. Shake bottle for 10 secs before use. Initially 20mg once daily in the AM. May increase by 10–20mg per week if needed; max 60mg daily. Discontinue if no improvement seen after dose adjustment over 1 month. Switching from other methylphenidate products: discontinue and follow Quillivant XR titration schedule.
Quillivant Xr Contraindications
Contraindications
During or within 14 days of MAOIs.
Quillivant Xr Boxed Warnings
Boxed Warning
Abuse and dependence.
Quillivant Xr Warnings/Precautions
Warnings/Precautions
Do not substitute for other methylphenidate products on a mg-per-mg basis. High potential for abuse and dependence; monitor. Increased risk of sudden death, stroke, and MI; assess for presence of cardiac disease before initiating. Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, and other cardiac problems. Pre-existing psychotic disorder. Bipolar disorder. Screen for risk factors in developing manic episode prior to initiating. Consider discontinuing if new psychotic or manic symptoms occur. Peripheral vasculopathy, including Raynaud's phenomenon; monitor for digital changes. Monitor growth (in children), BP, HR. Reduce dose or discontinue if paradoxical aggravation of symptoms occurs. Write ℞ for smallest practical amount. Reevaluate periodically. Pregnancy. Nursing mothers: monitor infants.
Quillivant Xr Pharmacokinetics
See Literature
Quillivant Xr Interactions
Interactions
See Contraindications. Hypertensive crisis with MAOIs. May antagonize antihypertensive agents; monitor and adjust dose of antihypertensives as needed. Concomitant risperidone may increase risk of extrapyramidal symptoms; monitor.
Quillivant Xr Adverse Reactions
Adverse Reactions
Appetite decreased, insomnia, nausea, vomiting, dyspepsia, abdominal pain, weight decreased, anxiety, dizziness, irritability, affect lability, tachycardia, hypertension; priapism.
Quillivant Xr Clinical Trials
See Literature
Quillivant Xr Note
Not Applicable
Quillivant Xr Patient Counseling
See Literature
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