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Pulmozyme Generic Name & Formulations
Legal Class
Rx
General Description
Dornase alfa (recombinant human DNase) 1mg/mL; soln for inh; preservative-free.
How Supplied
Amps (2.5mL)—30
Manufacturer
Pulmozyme Indications
Indications
Management of cystic fibrosis in conjunction with standard therapies to improve pulmonary function.
Pulmozyme Dosage and Administration
Adults and Children
<3months: not recommended. Use appropriate nebulizer. Do not dilute. >5yrs: 2.5mg once daily via nebulization; may increase to 2.5mg twice daily (see literature).
Pulmozyme Contraindications
Not Applicable
Pulmozyme Boxed Warnings
Not Applicable
Pulmozyme Warnings/Precautions
Warnings/Precautions
For patients <5yrs of age, use only if there is a potential for benefit in pulmonary function or in risk of respiratory tract infection. Use only with recommended nebulizers. Pregnancy (Cat.B). Nursing mothers.
Pulmozyme Pharmacokinetics
See Literature
Pulmozyme Interactions
Interactions
Do not mix with other drugs in nebulizer.
Pulmozyme Adverse Reactions
Adverse Reactions
Pharyngitis, voice alteration, laryngitis, rash, chest pain, conjunctivitis.
Pulmozyme Clinical Trials
See Literature
Pulmozyme Note
Not Applicable
Pulmozyme Patient Counseling
See Literature
