• Lung surfactants/mucolytics

Pulmozyme Generic Name & Formulations

General Description

Dornase alfa (recombinant human DNase) 1mg/mL; soln for inh; preservative-free.

How Supplied

Amps (2.5mL)—30


Pulmozyme Indications


Management of cystic fibrosis in conjunction with standard therapies to improve pulmonary function.

Pulmozyme Dosage and Administration

Adults and Children

<3months: not recommended. Use appropriate nebulizer. Do not dilute. >5yrs: 2.5mg once daily via nebulization; may increase to 2.5mg twice daily (see literature).

Pulmozyme Contraindications

Not Applicable

Pulmozyme Boxed Warnings

Not Applicable

Pulmozyme Warnings/Precautions


For patients <5yrs of age, use only if there is a potential for benefit in pulmonary function or in risk of respiratory tract infection. Use only with recommended nebulizers. Pregnancy (Cat.B). Nursing mothers.

Pulmozyme Pharmacokinetics

See Literature

Pulmozyme Interactions


Do not mix with other drugs in nebulizer.

Pulmozyme Adverse Reactions

Adverse Reactions

Pharyngitis, voice alteration, laryngitis, rash, chest pain, conjunctivitis.

Pulmozyme Clinical Trials

See Literature

Pulmozyme Note

Not Applicable

Pulmozyme Patient Counseling

See Literature