Asthma/COPD:

Indications for PROVENTIL HFA:

Bronchospasm.

Adults and Children:

<4yrs: Use other forms. ≥4yrs: 2 inh every 4–6hrs as needed; 1 inh every 4hrs may suffice. Exercise-induced bronchospasm: 2 inh 15–30 minutes before exercise.

Warnings/Precautions:

Avoid excessive use. Sensitivity to sympathomimetics. Discontinue if paradoxical bronchospasm or cardiovascular effects occur. Cardiovascular disease (eg, coronary insufficiency, arrhythmias, hypertension). Diabetes. Ketoacidosis. Hyperthyroidism. Seizure disorders. Reevaluate periodically. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Pharmacologic Class:

Beta-2 agonist.

Interactions:

Avoid MAOIs, tricyclics within 14 days (increased cardiovascular effects). Oral sympathomimetics: not recommended. Antagonized by β-blockers. Monitor digoxin. Caution with other drugs that may lower serum potassium (eg, diuretics).

Adverse Reactions:

Tremor, nervousness, headache, dizziness, excitement, insomnia, weakness, tachycardia, epistaxis, hypokalemia, local irritation, paradoxical bronchospasm; immediate hypersensitivity reactions (eg, rash, urticaria, angioedema); rare; metabolic acidosis.

Metabolism:

Hepatic.

Elimination:

Renal.

Generic Availability:

NO

How Supplied:

Inhalation aerosol—6.7g (200 inh)