Propranolol Hcl Injection

  • CHF and arrhythmias

Propranolol Hcl Injection Generic Name & Formulations

General Description

Propranolol HCl 1mg/mL; soln for IV inj.

Pharmacological Class


How Supplied

Contact supplier.

Propranolol Hcl Injection Indications


Supraventricular arrhythmias (see literature). Ventricular tachycardias (not first-line). Tachyarrhythmias of digitalis intoxication. Resistant tachyarrythmias due to excessive catecholamine action during anesthesia.

Propranolol Hcl Injection Dosage and Administration


Usual dose: 1–3mg IV at a rate of 1mg/min. If necessary, a second dose may be given after 2 minutes. Thereafter, additional drug should not be given in less than 4 hours. Transfer to oral therapy as soon as possible.


Not recommended.

Propranolol Hcl Injection Contraindications


Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Cardiogenic shock.

Propranolol Hcl Injection Boxed Warnings

Not Applicable

Propranolol Hcl Injection Warnings/Precautions


CHF. Wolff-Parkinson-White syndrome. Renal or hepatic dysfunction. Bronchospastic disease, COPD. Diabetes. Hyperthyroidism. Surgery. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.

Propranolol Hcl Injection Pharmacokinetics

See Literature

Propranolol Hcl Injection Interactions


Potentiated by CNS depressants, other antihypertensives, haloperidol, propafenone, quinidine, disopyramide, amiodarone. Bradycardia with catecholamine-depleting drugs (eg, reserpine). Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. Caution with drugs that slow A-V nodal conduction (eg, calcium channel blockers, digitalis, lidocaine). Potentiates theophylline, antipyrine, lidocaine. Antihypertensive effects of clonidine may be antagonized. Concomitant methoxyflurane, trichloroethylene may depress myocardial contractility. Concomitant thyroxine may result in lower T3 concentration. May block epinephrine. May interfere with glaucoma screening tests. Monitor prothrombin time with warfarin.

Propranolol Hcl Injection Adverse Reactions

Adverse Reactions

Bradycardia, CHF, intensification of AV block, hypotension, CNS effects, GI upset, pharyngitis, rash, bronchospasm, blood dyscrasias; rare: SLE.

Propranolol Hcl Injection Clinical Trials

See Literature

Propranolol Hcl Injection Note

Not Applicable

Propranolol Hcl Injection Patient Counseling

See Literature