• Corticosteroid-responsive disorders

Prednisone Generic Name & Formulations

General Description

Prednisone 1mg, 2.5mg, 5mg, 10mg, 20mg, 50mg; scored tabs.

Pharmacological Class


How Supplied

Contact supplier.

Prednisone Indications


Corticosteroid-responsive disorders.

Prednisone Dosage and Administration

Adults and Children

See full labeling. Initially 5–60mg daily.

Prednisone Contraindications


Systemic fungal infections. Live vaccines.

Prednisone Boxed Warnings

Not Applicable

Prednisone Warnings/Precautions


Tuberculosis. Latent amebiasis. Strongyloides infestation. Hypothyroidism. Ocular herpes simplex. Cirrhosis. Renal insufficiency. If exposed to chickenpox or measles, consider prophylactic passive immune therapy. Ulcerative colitis if perforation pending. Peptic ulcer. Diverticulitis. Intestinal anastomoses. Myasthenia gravis. Hypertension. Osteoporosis. Diabetes. Kaposi's sarcoma. Supplement with additional steroids in physiologic stress. Avoid abrupt cessation. May increase risk and mask signs of infection. May cause electrolyte imbalances, adrenocortical insufficiency, psychotic derangements. Alternate, intermittent, or single-daily doses at 8AM minimize adrenal suppression. Use lowest effective dose. Monitor weight, growth, fluid and electrolyte balance. Pregnancy. Nursing mothers.

Prednisone Pharmacokinetics

See Literature

Prednisone Interactions


Barbiturates, hydantoins, rifampin, other hepatic enyzme inducers may decrease effects. Potentiated by ketoconazole, troleandomycin. Excretion of high-dose aspirin increased. Caution with diuretics, digoxin, aspirin in hypoprothrombinemia. Potentiated by oral contraceptives. Monitor oral anticoagulants.

Prednisone Adverse Reactions

Adverse Reactions

HPA axis suppression, increased susceptibility to infection, glaucoma, cataracts, secondary infections, hypokalemia, hypocalcemia, hypernatremia, hypertension, CHF, psychic disorders, myopathy, osteoporosis, peptic ulcer, dermal atrophy, increased intracranial pressure, carbohydrate intolerance.

Prednisone Clinical Trials

See Literature

Prednisone Note


Formerly known under the brand names Deltasone, Meticorten, Orasone, Paracort.

Prednisone Patient Counseling

See Literature