Prednisone Intensol

  • Corticosteroid-responsive disorders

Prednisone Intensol Generic Name & Formulations

General Description

Prednisone 5mg; per 1mL; concentrated soln; contains alcohol 30%.

Pharmacological Class


How Supplied

Soln—120mL, 500mL; Intensol—30mL (w. dropper)

Prednisone Intensol Indications


Corticosteroid-responsive disorders.

Prednisone Intensol Dosage and Administration

Adults and Children

See literature. Initially 5mg–60mg daily. Intensol: mix with liquid or semi-solid food.

Prednisone Intensol Contraindications


Systemic fungal infections. Live vaccines.

Prednisone Intensol Boxed Warnings

Not Applicable

Prednisone Intensol Warnings/Precautions


Tuberculosis. Latent amebiasis. Strongyloides infestation. Hypothyroidism. Ocular herpes simplex. Cirrhosis. Renal insufficiency. If exposed to chickenpox or measles, consider prophylactic passive immune therapy. Ulcerative colitis if perforation pending. Peptic ulcer. Diverticulitis. Intestinal anastomoses. Myasthenia gravis. Hypertension. Osteoporosis. Diabetes. Kaposi's sarcoma. Supplement with additional steroids in physiologic stress. Avoid abrupt cessation. May increase risk and mask signs of infection. May cause electrolyte imbalances, adrenocortical insufficiency, psychotic derangements. Alternate, intermittent, or single-daily doses at 8AM minimize adrenal suppression. Use lowest effective dose. Monitor weight, growth, fluid and electrolyte balance. Pregnancy. Nursing mothers.

Prednisone Intensol Pharmacokinetics

See Literature

Prednisone Intensol Interactions


Barbiturates, hydantoins, rifampin, other hepatic enyzme inducers may decrease effects. Potentiated by ketoconazole, troleandomycin. Excretion of high-dose aspirin increased. Caution with diuretics, digoxin, aspirin in hypoprothrombinemia. Potentiated by oral contraceptives. Monitor oral anticoagulants.

Prednisone Intensol Adverse Reactions

Adverse Reactions

HPA axis suppression, increased susceptibility to infection, glaucoma, cataracts, secondary infections, hypokalemia, hypocalcemia, hypernatremia, hypertension, CHF, psychic disorders, myopathy, osteoporosis, peptic ulcer, dermal atrophy, increased intracranial pressure, carbohydrate intolerance.

Prednisone Intensol Clinical Trials

See Literature

Prednisone Intensol Note

Not Applicable

Prednisone Intensol Patient Counseling

See Literature