• Ocular allergy/inflammation

Pred-g Generic Name & Formulations

General Description

Prednisolone acetate 1%, gentamicin (as sulfate) 0.3%; oph. susp; contains benzalkonium chloride.

Pharmacological Class

Steroid + aminoglycoside.

See Also

How Supplied

Susp—5mL, 10mL; Oint—3.5g


Mechanism of Action

Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticosteroids may inhibit the body’s defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case.

Pred-g Indications


Ocular inflammation associated with infection.

Pred-g Dosage and Administration


1 drop 2–4 times daily; max 20mL for initial ℞.


Not established.

Pred-g Contraindications


Fungal, viral or mycobacterial infections.

Pred-g Boxed Warnings

Not Applicable

Pred-g Warnings/Precautions


Not for uncomplicated removal of foreign body. Corneal or scleral thinning. Glaucoma. Monitor for secondary infections, cataracts, and intraocular pressure in prolonged use. May mask signs of infection. Avoid abrupt cessation. Pregnancy. Nursing mothers: not recommended.

Pred-g Pharmacokinetics


Hepatic (prednisolone).


Renal. Half-life: 2.1–3.5 hours (prednisolone).

Pred-g Interactions

Not Applicable

Pred-g Adverse Reactions

Adverse Reactions

In prolonged use increased intraocular pressure, cataracts, corneal perforation, optic nerve damage, secondary infections. Ocular discomfort (eg, burning, stinging, hyperemia, pain, discharge, edema, irritation), visual impairment, blurry vision, foreign body sensation in eyes, dysgeusia, punctate keratitis, delayed wound healing, hypersensitivity or allergic skin reactions.

Pred-g Clinical Trials

See Literature

Pred-g Note

Not Applicable

Pred-g Patient Counseling

See Literature