Pred-g Oph Oint Generic Name & Formulations
Prednisolone acetate 0.6%, gentamicin (as sulfate) 0.3%.
Steroid + aminoglycoside.
Susp—5mL, 10mL; Oint—3.5g
Mechanism of Action
Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticosteroids may inhibit the body’s defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case.
Pred-g Oph Oint Indications
Ocular inflammation associated with infection.
Pred-g Oph Oint Dosage and Administration
½ inch 1–3 times daily; max 8g for initial ℞.
Pred-g Oph Oint Contraindications
Fungal, viral or mycobacterial infections.
Pred-g Oph Oint Boxed Warnings
Pred-g Oph Oint Warnings/Precautions
Not for uncomplicated removal of foreign body. Corneal or scleral thinning. Glaucoma. Monitor for secondary infections, cataracts, and intraocular pressure in prolonged use. May mask signs of infection. Avoid abrupt cessation. Pregnancy. Nursing mothers: not recommended.
Pred-g Oph Oint Pharmacokinetics
Renal. Half-life: 2.1–3.5 hours (prednisolone).
Pred-g Oph Oint Interactions
Pred-g Oph Oint Adverse Reactions
In prolonged use increased intraocular pressure, cataracts, corneal perforation, optic nerve damage, secondary infections. Ocular discomfort (eg, burning, stinging, hyperemia, pain, discharge, edema, irritation), visual impairment, blurry vision, foreign body sensation in eyes, dysgeusia, punctate keratitis, delayed wound healing, hypersensitivity or allergic skin reactions.
Pred-g Oph Oint Clinical Trials
Pred-g Oph Oint Note
Pred-g Oph Oint Patient Counseling