Pred-g Oph Oint

  • Ocular allergy/inflammation

Pred-g Oph Oint Generic Name & Formulations

General Description

Prednisolone acetate 0.6%, gentamicin (as sulfate) 0.3%.

Pharmacological Class

Steroid + aminoglycoside.

See Also

How Supplied

Susp—5mL, 10mL; Oint—3.5g


Mechanism of Action

Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticosteroids may inhibit the body’s defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case.

Pred-g Oph Oint Indications


Ocular inflammation associated with infection.

Pred-g Oph Oint Dosage and Administration


½ inch 1–3 times daily; max 8g for initial ℞.


Not established.

Pred-g Oph Oint Contraindications


Fungal, viral or mycobacterial infections.

Pred-g Oph Oint Boxed Warnings

Not Applicable

Pred-g Oph Oint Warnings/Precautions


Not for uncomplicated removal of foreign body. Corneal or scleral thinning. Glaucoma. Monitor for secondary infections, cataracts, and intraocular pressure in prolonged use. May mask signs of infection. Avoid abrupt cessation. Pregnancy. Nursing mothers: not recommended.

Pred-g Oph Oint Pharmacokinetics


Hepatic (prednisolone).


Renal. Half-life: 2.1–3.5 hours (prednisolone).

Pred-g Oph Oint Interactions

Not Applicable

Pred-g Oph Oint Adverse Reactions

Adverse Reactions

In prolonged use increased intraocular pressure, cataracts, corneal perforation, optic nerve damage, secondary infections. Ocular discomfort (eg, burning, stinging, hyperemia, pain, discharge, edema, irritation), visual impairment, blurry vision, foreign body sensation in eyes, dysgeusia, punctate keratitis, delayed wound healing, hypersensitivity or allergic skin reactions.

Pred-g Oph Oint Clinical Trials

See Literature

Pred-g Oph Oint Note

Not Applicable

Pred-g Oph Oint Patient Counseling

See Literature