Electrolyte disturbances:

Indications for Potassium Chloride Ext-Rel Tabs:

Hypokalemia, including that caused by diuretics. Digitalis intoxication without AV block.


Do not crush or chew. Take with meals and fluid. Prophylaxis: 20mEq daily. Treatment: 40–100mEq daily in divided doses.


Not recommended.


Hyperkalemia. Chronic renal disease. Acute dehydration. Heat cramps. Severe tissue destruction. Adrenal insufficiency. Familial periodic paralysis. Acidosis (potassium chloride products). Alkalosis (potassium bicarbonate products). Esophageal compression due to enlarged left atrium. Decreased GI motility.


Discontinue if GI bleed, ulceration, or other disturbances occur. Renal or cardiac disease. Monitor potassium level, clinical status, acid-base balance, and ECG. Elderly. Pregnancy (Cat.C). Nursing mothers.


Avoid concomitant potassium-sparing diuretics. Monitor for hyperkalemia with drugs that inhibit the renin-angiotensin-aldosterone sytem (eg, ACE inhibitors, ARBs, spironolactone, eplerenone, aliskiren), or NSAIDs. Anticholinergics, other agents that decrease GI motility increase risk of serious GI reactions with tablets.

Adverse Reactions:

Hyperkalemia, GI discomfort and irritation, diarrhea, rash (rare). Esophageal and GI ulceration, bleeding, obstruction, perforation.


Formerly known under the brand name Klotrix.

How Supplied:

Contact supplier.