• Labor and delivery

Pitocin Generic Name & Formulations

General Description

Oxytocin 10Units/mL; IV or IM inj.

How Supplied

Single-dose vial (1mL)—25; Multi-dose vial (10mL)—1, 25

Pitocin Indications


Initiation or improvement of uterine contractions in vaginal delivery. Adjunct in abortion. Control of postpartum bleeding.

Pitocin Dosage and Administration


Induction of labor: individualize. Initially 0.5–1milliunit/minute (see literature); adjust by 1–2 milliunits/minute at 30–60 minute intervals. Usual max at term: 9–10 milliunits/minute. Bleeding: IV, see literature. IM: 10Units after delivery of placenta. Abortion: see literature.


Not applicable.

Pitocin Contraindications


In anteparum use: Cephalopelvic disproportion. Unfavorable fetal position. When surgical intervention necessary. Fetal distress if labor is not imminent. Unsatisfactory progress in presence of adequate uterine activity. Hyperactive or hypertonic uterus. Invasive cervical carcinoma, active herpes genitalis, total placenta previa, vasa previa, cord presentation or prolapse or other cases where vaginal delivery is contraindicated or if predisposition for uterine rupture exists.

Pitocin Boxed Warnings

Boxed Warning

Not for elective induction of labor.

Pitocin Warnings/Precautions


Use only in presence of qualified personnel. Monitor intrauterine pressure, fetal heart rate, maternal blood pressure.

Pitocin Pharmacokinetics

See Literature

Pitocin Interactions


Avoid use within 4 hours of prophylactic vasoconstriction with caudal block anesthesia. Avoid cyclopropane anesthetics.

Pitocin Adverse Reactions

Adverse Reactions

Maternal: anaphylaxis, postpartum or subarachnoid hemorrhage, arrhythmias, fatal afibrinogenemia, nausea, vomiting, premature ventricular contraction, pelvic hematoma, water intoxication, hypersensitivity resulting in uterine hypertonicity, spasm, tetany, or rupture. Fetal: bradycardia, arrhythmias, CNS damage, seizure, low Apgar scores, jaundice, retinal hemorrhage, death.

Pitocin Clinical Trials

See Literature

Pitocin Note

Not Applicable

Pitocin Patient Counseling

See Literature