Oxybutynin Chloride

  • Overactive bladder/enuresis

Oxybutynin Chloride Generic Name & Formulations

General Description

Oxybutynin chloride 5mg; scored tabs.

Pharmacological Class


How Supplied

Contact supplier.

Oxybutynin Chloride Indications


Symptoms of bladder instability associated with voiding in patients with uninhibited neurogenic or reflex neurogenic bladder (eg, urinary urgency, frequency, leakage, urge incontinence, dysuria).

Oxybutynin Chloride Dosage and Administration


5mg 2–3 times a day; max 20mg/day.


<5yrs: not recommended. ≥5yrs: 5mg twice daily; max 15mg/day.

Oxybutynin Chloride Contraindications


Uncontrolled glaucoma. GI obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Severe colitis. Myasthenia gravis. Megacolon. Toxic megacolon in ulcerative colitis. Obstructive uropathies. Unstable cardiovascular status in acute hemorrhage.

Oxybutynin Chloride Boxed Warnings

Not Applicable

Oxybutynin Chloride Warnings/Precautions


Activities requiring mental alertness. Diarrhea. Hepatic or renal disease. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hiatal hernia. GI or GU obstruction. Ulcerative colitis. Exposure to extreme heat. Elderly. Pregnancy (Cat.B). Nursing mothers.

Oxybutynin Chloride Pharmacokinetics

See Literature

Oxybutynin Chloride Interactions


Potentiates drowsiness with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics. May be potentiated by CYP3A4 inhibitors. Decreases GI motility, possibly affecting absorption of other drugs.

Oxybutynin Chloride Adverse Reactions

Adverse Reactions

Dry mouth, constipation, somnolence, headache, diarrhea, nausea, tachycardia, blurred vision, dry eyes, other anticholinergic effects.

Oxybutynin Chloride Clinical Trials

See Literature

Oxybutynin Chloride Note


Formerly known under the brand name Ditropan.

Oxybutynin Chloride Patient Counseling

See Literature