Ovidrel

— THERAPEUTIC CATEGORIES —
  • Infertility

Ovidrel Generic Name & Formulations

General Description

Choriogonadotropin alfa (r-hCG) 250mcg/0.5mL; liq for SC inj.

How Supplied

Prefilled syringe—1

Manufacturer

Ovidrel Indications

Indications

Induction of final follicular maturation and early luteinization in infertile women as part of an Assisted Reproductive Technology (ART) program. Ovulation induction where infertility is not due to ovarian failure.

Ovidrel Dosage and Administration

Adult

250mg SC one day after last dose of follicle-stimulating agent, if adequate follicular development is evident, and only if there is no evidence of excessive ovarian response (e.g., significant ovarian enlargement, excessive estradiol production, multiple follicular development seen on ultrasound).

Children

Not applicable.

Ovidrel Contraindications

Contraindications

Ovarian enlargement and excessive follicular recruitment while undergoing menotropin therapy. Primary ovarian failure. Uncontrolled thyroid or adrenal dysfunction. Uncontrolled intracranial lesion (eg, pituitary tumor). Abnormal genital bleeding. Ovarian cyst or enlargement. Sex hormone-dependent tumors of reproductive system. Pregnancy (Cat.X).

Ovidrel Boxed Warnings

Not Applicable

Ovidrel Warnings/Precautions

Warnings/Precautions

Do complete gynecological and endocrinological exam first. Cardiac or renal disease. Epilepsy. Migraine. Asthma. Nursing mothers.

Ovidrel Pharmacokinetics

See Literature

Ovidrel Interactions

Ovidrel Adverse Reactions

Adverse Reactions

Ovarian hyperstimulation syndrome (discontinue if occurs) or enlargement, ascites, pleural effusion, ovarian cyst rupture, abdominal pain, multiple births, arterial thromboembolism, headache, irritability, restlessness, depression, fatigue, edema, local reactions.

Ovidrel Clinical Trials

See Literature

Ovidrel Note

Not Applicable

Ovidrel Patient Counseling

See Literature