• Ear infections (topicals)

Otiprio Generic Name & Formulations

General Description

Ciprofloxacin 6% (60mg/mL); otic susp; preservative-free.

Pharmacological Class

Antibiotic (quinolone).

How Supplied

Single-patient use vial—1mL


Generic Availability


Otiprio Indications


Bilateral otitis media with effusion undergoing tympanostomy tube placement. Acute otitis externa due to P. aeruginosa and S. aureus.

Otiprio Dosage and Administration

Adults and Children

<6mos: not established. For intratympanic or otic administration only. ≥6mos: Otitis media: give as one 0.1mL (6mg) single dose into each affected ear, following suctioning of middle ear effusion. Otitis externa: give as one 0.2mL (12mg) single dose to the external ear canal of each affected ear.

Otiprio Contraindications

Not Applicable

Otiprio Boxed Warnings

Not Applicable

Otiprio Warnings/Precautions


Potential for microbial overgrowth (eg, bacteria, fungi); if infections occur, use alternatives. Pregnancy.

Otiprio Pharmacokinetics

See Literature

Otiprio Interactions

Otiprio Adverse Reactions

Adverse Reactions

Nasopharyngitis, irritability, ear pruritus, headache, otitis media, ear discomfort.

Otiprio Clinical Trials

See Literature

Otiprio Note

Not Applicable

Otiprio Patient Counseling

See Literature