Nyquil Cold & Flu

  • Cough and cold

Nyquil Cold & Flu Generic Name & Formulations

General Description

Acetaminophen 325mg, doxylamine succinate 6.25mg, dextromethorphan HBr 15mg; per liquiCap.

Pharmacological Class

Analgesic + antihistamine + antitussive.

How Supplied

LiquiCaps—12, 20, 40, 60; Liq—6oz, 10oz

Nyquil Cold & Flu Indications


Cough, sore throat, rhinorrhea, fever, headache, minor aches and pains.

Nyquil Cold & Flu Dosage and Administration


2 caps every 6hrs; max 4 doses/24hrs.


Not recommended.

Nyquil Cold & Flu Contraindications


During or within 14 days of MAOIs. Concomitant other acetaminophen products.

Nyquil Cold & Flu Boxed Warnings

Not Applicable

Nyquil Cold & Flu Warnings/Precautions


Hepatic dysfunction. Glaucoma. GI or GU obstruction. Asthma. Lower respiratory disoders. Pregnancy. Nursing mothers.

Nyquil Cold & Flu Pharmacokinetics

See Literature

Nyquil Cold & Flu Interactions


See Contraindications. Hypertensive crisis with MAOIs. Increased risk of hepatotoxicity with ≥3 alcoholic drinks/day; avoid. Increased CNS effects with other CNS depressants.

Nyquil Cold & Flu Adverse Reactions

Adverse Reactions

Drowsiness, anticholinergic effects, excitability in children, hepatotoxicity (overdosage).

Nyquil Cold & Flu Clinical Trials

See Literature

Nyquil Cold & Flu Note

Not Applicable

Nyquil Cold & Flu Patient Counseling

See Literature