Constipation and bowel cleansers:
Indications for: NuLYTELY
Bowel cleansing before colonoscopy.
May consume water or clear liquids during and after completion of bowel prep up until 2hrs before procedure. Drink 240mL orally every 10 mins or 20–30mL/min by NG tube until rectal effluent is clear or 4L consumed. May interrupt if severe GI disturbances occur.
<6 months: not recommended. ≥6 months: May consume water or clear liquids during and after completion of bowel prep up until 2hrs before procedure. Drink 25mL/kg per hour orally or by NG tube until rectal effluent is clear or 4L consumed. May interrupt if severe GI disturbances occur.
GI obstruction. Bowel perforation. Gastric retention. Ileus. Toxic colitis or megacolon.
Not for direct ingestion. Correct fluid/electrolyte abnormalities prior to initiation. History of prolonged QT, uncontrolled arrhythmias, recent MI, unstable angina, CHF, or cardiomyopathy: increased risk of arrhythmias; consider ECGs at pre-dose and post-colonoscopy. History or risk of seizures. Renal impairment; monitor baseline and post-colonoscopy electrolytes, creatinine, BUN. Inflammatory bowel disease. Rule out suspected GI obstruction/perforation before administering. Severe ulcerative colitis. Impaired gag reflex. Semi- or unconscious patients. Risk for regurgitation or aspiration. Monitor young children (<2yrs) for hypoglycemia. Maintain adequate hydration. Pregnancy. Nursing mothers.
Avoid concomitant with starch-based thickeners. Caution with drugs that increase risk of fluid/electrolyte abnormalities, arrhythmias or QT prolongation. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal, known or suspected hyponatremia: may increase risk of seizures. Concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Avoid concomitant stimulant laxatives (eg, bisacodyl, sodium picosulfate). Oral drugs administered within 1hr of start of Nulytely may not be absorbed.
Nausea, abdominal fullness and bloating, cramps, vomiting, anal irritation; seizures, arrhythmias, mucosal ulcerations and ischemic colitis. Children: also dehydration or hypokalemia.
Generic Drug Availability:
Disposable jug (4L)—1