Nulev

— THERAPEUTIC CATEGORIES —
  • Cough and cold
  • Hyperacidity, GERD, and ulcers
  • Parkinsonism
  • Poisoning/overdose
  • Urinary tract discomfort

Nulev Generic Name & Formulations

General Description

Hyoscyamine sulfate 0.125mg; chewable melt tabs; peppermint flavor.

Pharmacological Class

Anticholinergic.

How Supplied

Tabs—100

Manufacturer

Nulev Indications

Indications

As a drying agent in the relief of symptoms of acute rhinitis.

Nulev Dosage and Administration

Adults and Children

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Nulev Contraindications

Contraindications

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Nulev Boxed Warnings

Not Applicable

Nulev Warnings/Precautions

Warnings/Precautions

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Nulev Pharmacokinetics

See Literature

Nulev Interactions

Interactions

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Nulev Adverse Reactions

Adverse Reactions

Anticholinergic effects (eg, drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

Nulev Clinical Trials

See Literature

Nulev Note

Not Applicable

Nulev Patient Counseling

See Literature

Nulev Generic Name & Formulations

General Description

Hyoscyamine sulfate 0.125mg; chewable melt tabs; peppermint flavor.

Pharmacological Class

Anticholinergic.

How Supplied

Tabs—100

Manufacturer

Nulev Indications

Indications

Adjunct in irritable bowel syndrome, peptic ulcer, spastic or functional GI disorders, neurogenic bowel disorders, colic.

Nulev Dosage and Administration

Adults and Children

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Nulev Contraindications

Contraindications

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Nulev Boxed Warnings

Not Applicable

Nulev Warnings/Precautions

Warnings/Precautions

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Nulev Pharmacokinetics

See Literature

Nulev Interactions

Interactions

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Nulev Adverse Reactions

Adverse Reactions

Anticholinergic effects (eg, drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

Nulev Clinical Trials

See Literature

Nulev Note

Not Applicable

Nulev Patient Counseling

See Literature

Nulev Generic Name & Formulations

General Description

Hyoscyamine sulfate 0.125mg; chewable melt tabs; peppermint flavor.

Pharmacological Class

Anticholinergic.

How Supplied

Tabs—100

Manufacturer

Nulev Indications

Indications

Parkinsonism: to reduce rigidity and tremors and to control associated sialorrhea and hyperhidrosis.

Nulev Dosage and Administration

Adults and Children

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Nulev Contraindications

Contraindications

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Nulev Boxed Warnings

Not Applicable

Nulev Warnings/Precautions

Warnings/Precautions

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Nulev Pharmacokinetics

See Literature

Nulev Interactions

Interactions

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Nulev Adverse Reactions

Adverse Reactions

Anticholinergic effects (eg, drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

Nulev Clinical Trials

See Literature

Nulev Note

Not Applicable

Nulev Patient Counseling

See Literature

Nulev Generic Name & Formulations

General Description

Hyoscyamine sulfate 0.125mg; chewable melt tabs; peppermint flavor.

Pharmacological Class

Anticholinergic.

How Supplied

Tabs—100

Manufacturer

Nulev Indications

Indications

Anticholinesterase poisoning.

Nulev Dosage and Administration

Adults and Children

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Nulev Contraindications

Contraindications

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Nulev Boxed Warnings

Not Applicable

Nulev Warnings/Precautions

Warnings/Precautions

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Nulev Pharmacokinetics

See Literature

Nulev Interactions

Interactions

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Nulev Adverse Reactions

Adverse Reactions

Anticholinergic effects (eg, drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

Nulev Clinical Trials

See Literature

Nulev Note

Not Applicable

Nulev Patient Counseling

See Literature

Nulev Generic Name & Formulations

General Description

Hyoscyamine sulfate 0.125mg; chewable melt tabs; peppermint flavor.

Pharmacological Class

Anticholinergic.

How Supplied

Tabs—100

Manufacturer

Nulev Indications

Indications

Lower urinary tract spasm.

Nulev Dosage and Administration

Adults and Children

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Nulev Contraindications

Contraindications

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Nulev Boxed Warnings

Not Applicable

Nulev Warnings/Precautions

Warnings/Precautions

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Nulev Pharmacokinetics

See Literature

Nulev Interactions

Interactions

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Nulev Adverse Reactions

Adverse Reactions

Anticholinergic effects (eg, drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

Nulev Clinical Trials

See Literature

Nulev Note

Not Applicable

Nulev Patient Counseling

See Literature