Nizatidine

— THERAPEUTIC CATEGORIES —
  • Hyperacidity, GERD, and ulcers

Nizatidine Generic Name & Formulations

General Description

Nizatidine 150mg; caps.

Pharmacological Class

H2 blocker.

How Supplied

Contact supplier

Nizatidine Indications

Indications

Active duodenal ulcer. Maintenance of healed duodenal ulcer. Benign gastric ulcer. Gastroesophageal reflux disease (GERD): including heartburn and erosive and ulcerative esophagitis.

Nizatidine Dosage and Administration

Adult

Active duodenal or benign gastric ulcer: 300mg daily at bedtime or 150mg twice daily, both for up to 8 weeks. Maintenance: 150mg daily at bedtime. GERD: 150mg twice daily for up to 12 weeks. Renal impairment (CrCl ≤50mL/min): reduce dose (see full labeling).

Children

<12yrs: not established. Use oral soln. Erosive esophagitis, GERD (≥12yrs): 150mg twice daily for up to 8 weeks; max 300mg/day. Renal impairment (CrCl ≤50mL/min): reduce dose (see full labeling).

Nizatidine Contraindications

Not Applicable

Nizatidine Boxed Warnings

Not Applicable

Nizatidine Warnings/Precautions

Warnings/Precautions

Rule out malignant gastric ulceration. Renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Nizatidine Pharmacokinetics

See Literature

Nizatidine Interactions

Interactions

May elevate serum salicylate levels in high-dose aspirin patients.

Nizatidine Adverse Reactions

Adverse Reactions

Headache, anemia, diarrhea, dizziness, sweating, rhinitis, urticaria.

Nizatidine Clinical Trials

See Literature

Nizatidine Note

Notes

Formerly known under the brand name Axid.

Nizatidine Patient Counseling

See Literature