Indications for NITROMIST:

Acute attacks and prophylaxis of angina.

Adult Dosage:

1–2 sprays at onset of attack, on or under tongue while sitting; may repeat every 5 minutes as needed; max 3 sprays/15 minutes. May use prophylactically 5–10 minutes before exertion. Do not inhale spray. Do not rinse mouth for 5–10 minutes after use.

Children Dosage:

Not established.

NITROMIST Contraindications:

Concomitant PDE5 inhibitors (eg, sildenafil, vardenafil, tadalafil), riociguat. Severe anemia. Increased intracranial pressure.

NITROMIST Warnings/Precautions:

Volume depletion. Hypotension. Acute MI. CHF. Hypertrophic cardiomyopathy. Monitor for tolerance. Product is flammable. Elderly. Pregnancy (Cat.C). Nursing mothers.

NITROMIST Classification:


NITROMIST Interactions:

See Contraindications. Hypotension potentiated with PDE5 inhibitors, riociguat, antihypertensives, β-blockers, calcium channel blockers, alcohol. May be potentiated by aspirin. Nitroglycerin (IV) may antagonize t-PA, heparin (monitor APTT). Avoid concomitant ergotamine and related drugs. Do not use epinephrine to treat hypotension from nitrate overdose.

Adverse Reactions:

Headache (may be severe), flushing, rash, hypotension, syncope.

How Supplied:

Bottles—4.1g (90 metered sprays), 8.5g (230 metered sprays)