Nitro-dur

— THERAPEUTIC CATEGORIES —
  • Angina

Nitro-dur Generic Name & Formulations

General Description

Nitroglycerin 0.1mg/hr, 0.2mg/hr, 0.3mg/hr, 0.4mg/hr, 0.6mg/hr, 0.8mg/hr; transdermal patches.

Pharmacological Class

Nitrate.

How Supplied

Patch—30

Manufacturer

Nitro-dur Indications

Indications

Prophylaxis of angina. Not for acute attacks.

Nitro-dur Dosage and Administration

Adult

Initially one 0.2–0.4mg/hr patch for 12–14hr/day. Remove patch for 10–12hrs/day.

Children

Not established.

Nitro-dur Contraindications

Contraindications

Concomitant PDE-5 inhibitors (eg, sildenafil, tadalafil, vardenafil), riociguat.

Nitro-dur Boxed Warnings

Not Applicable

Nitro-dur Warnings/Precautions

Warnings/Precautions

Acute MI. Volume depletion. Hypotension. Heart failure. Hypertrophic cardiomyopathy. Reduce dose if hypotension occurs. Remove before defibrillation or cardioversion. Elderly. Pregnancy (Cat.C). Nursing mothers.

Nitro-dur Pharmacokinetics

See Literature

Nitro-dur Interactions

Interactions

See Contraindications. Severe hypotension with PDE-5 inhibitors, riociguat. Hypotension potentiated with alcohol, other vasodilators, calcium channel blockers.

Nitro-dur Adverse Reactions

Adverse Reactions

Headache, increased angina, lightheadedness, syncope, orthostatic hypotension, tachycardia, rash.

Nitro-dur Clinical Trials

See Literature

Nitro-dur Note

Not Applicable

Nitro-dur Patient Counseling

See Literature