Nifedipine Ext-rel

  • Hypertension

Nifedipine Ext-rel Generic Name & Formulations

General Description

Nifedipine 30mg, 60mg, 90mg; ext-rel tabs.

Pharmacological Class

Calcium channel blocker (CCB) (dihydropyridine).

How Supplied

Contact supplier

Nifedipine Ext-rel Indications



Nifedipine Ext-rel Dosage and Administration


Swallow whole on empty stomach. Initially 30mg once daily. Usual maintenance: 30–60mg once daily. Titrate over 7–14 days; max 90mg/day.


Not established.

Nifedipine Ext-rel Contraindications

Not Applicable

Nifedipine Ext-rel Boxed Warnings

Not Applicable

Nifedipine Ext-rel Warnings/Precautions


Aortic stenosis. Angina. Severe obstructive coronary artery disease. Heart failure. Surgery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Nifedipine Ext-rel Pharmacokinetics

See Literature

Nifedipine Ext-rel Interactions


Potentiates antihypertensives, digoxin, tacrolimus. Angina and heart failure possible with β-blockers. Potentiated by cimetidine, doxazosin, ketoconazole, valproic acid, grapefruit juice, other CYP3A4 inhibitors. Antagonized by rifampin, phenytoin, carbamazepine, St. John's wort, other CYP3A4 inducers. Monitor oral anticoagulants, quinidine. Hypotension possible with fentanyl.

Nifedipine Ext-rel Adverse Reactions

Adverse Reactions

Peripheral edema, headache, flushing, dizziness, fatigue, constipation, muscle cramps, rash; exacerbation of angina, heart failure (rare).

Nifedipine Ext-rel Clinical Trials

See Literature

Nifedipine Ext-rel Note


Formerly known under the brand name Adalat CC.

Nifedipine Ext-rel Patient Counseling

See Literature