Nicotrol Ns

  • Smoking

Nicotrol Ns Generic Name & Formulations

General Description

Nicotine 0.5mg/spray; aqueous nasal spray.

See Also

How Supplied

Inhaler 168 cartridges—1 (w. mouthpieces and case); Nasal Spray 10mL (200 sprays)—4 (w. metered spray pump)


Nicotrol Ns Indications


Adjunct in smoking cessation therapy.

Nicotrol Ns Dosage and Administration


Do not sniff, swallow, or inhale. Individualize. Usually 1–2 doses/hour; max 5 doses/hour, 40 doses/day for up to 3 months; may discontinue abruptly or taper.


Not recommended.

Nicotrol Ns Contraindications


Concurrent smoking or other nicotine products.

Nicotrol Ns Boxed Warnings

Not Applicable

Nicotrol Ns Warnings/Precautions


Sustained use (>6 months): not recommended. Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Bronchospastic disease. Severe reactive airway disease: not recommended. Hepatic or moderate/severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Esophagitis. Active gastric or peptic ulcers. Elderly. Low doses may be toxic to children and pets. Nasal Spray: nasal mucosal disorders. Pregnancy, labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.

Nicotrol Ns Pharmacokinetics

See Literature

Nicotrol Ns Interactions


Nasal Spray antagonized by nasal vasoconstrictors (eg, xylometazoline). Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.

Nicotrol Ns Adverse Reactions

Adverse Reactions

Local irritation, nausea, diarrhea, hiccup, dyspepsia, headache, dizziness, palpitations, hypertension.

Nicotrol Ns Clinical Trials

See Literature

Nicotrol Ns Note

Not Applicable

Nicotrol Ns Patient Counseling

See Literature