Nicotrol Inhaler

  • Smoking

Nicotrol Inhaler Generic Name & Formulations

General Description

Nicotine inhalation system 10mg (4mg delivered); per cartridge; contains menthol.

See Also

How Supplied

Inhaler 168 cartridges—1 (w. mouthpieces and case); Nasal Spray 10mL (200 sprays)—4 (w. metered spray pump)


Nicotrol Inhaler Indications


Adjunct in smoking cessation therapy.

Nicotrol Inhaler Dosage and Administration


Each cartridge lasts about 20 minutes with frequent continuous puffing and provides nicotine equivalent to about 2 cigarettes. Individualize. Use at least 6 cartridges/day for 1st 3–6 weeks; max 16 cartridges/day for 1st 12 weeks, then reduce gradually over 12 more weeks.


Not recommended.

Nicotrol Inhaler Contraindications


Concurrent smoking or other nicotine products.

Nicotrol Inhaler Boxed Warnings

Not Applicable

Nicotrol Inhaler Warnings/Precautions


Sustained use (>6 months): not recommended. Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Bronchospastic disease. Severe reactive airway disease: not recommended. Hepatic or moderate/severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Esophagitis. Active gastric or peptic ulcers. Elderly. Low doses may be toxic to children and pets. Nasal Spray: nasal mucosal disorders. Pregnancy, labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.

Nicotrol Inhaler Pharmacokinetics

See Literature

Nicotrol Inhaler Interactions


Nasal Spray antagonized by nasal vasoconstrictors (eg, xylometazoline). Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.

Nicotrol Inhaler Adverse Reactions

Adverse Reactions

Local irritation, nausea, diarrhea, hiccup, dyspepsia, headache, dizziness, palpitations, hypertension.

Nicotrol Inhaler Clinical Trials

See Literature

Nicotrol Inhaler Note

Not Applicable

Nicotrol Inhaler Patient Counseling

See Literature