• Smoking

Nicorette Generic Name & Formulations

General Description

Nicotine polacrilex 2mg, 4mg; chewing gum; sugar-free; contains sodium, calcium; mint, fresh mint, white ice mint, cinnamon surge, fruit chill, or original flavor.

How Supplied

Gum—20, 100, 110, 200; Lozenge—(mint, cherry)—72; (original)—108; Mini lozenge—20, 81, 108, 135


Nicorette Indications


Adjunct in smoking cessation therapy.

Nicorette Dosage and Administration


Start on quit day. Use 2mg if patient smoked first cigarette >30 mins after waking up; use 4mg if patient smoked first cigarette within 30 mins of waking up. Chew gum slowly until it tingles; park between cheek and gum; repeat until most of the tingle is gone (about 30 mins). ≥18yrs: Use 1 piece every 1–2hrs for 6 weeks (at least 9 pieces/day), then every 2–4hrs for 3 weeks, then every 4–8hrs for 3 weeks, then stop; max 24 pieces/day. If strong or frequent cravings, may use 2nd piece within the hour; avoid continuous use.


<18yrs: not recommended.

Nicorette Contraindications

Not Applicable

Nicorette Boxed Warnings

Not Applicable

Nicorette Warnings/Precautions


Cardiovascular disease, recent heart attack, irregular heart beat. Uncontrolled hypertension. Peptic ulcer disease. Diabetes. History of seizures. Sodium-restricted diet. Discontinue and evaluate if irregular heart beat, palpitations, mouth/teeth/jaw problems, persistent indigestion, severe sore throat, nicotine overdose symptoms, or allergic reactions occur. Keep out of reach of children and pets. Pregnancy. Nursing mothers.

Nicorette Pharmacokinetics

See Literature

Nicorette Interactions


Do not eat or drink for 15 mins before and during use. Concomitant other non-nicotine smoking cessation drug. Concomitant antidepressants or anti-asthmatic drugs; may need to adjust dose.

Nicorette Adverse Reactions

Adverse Reactions

Nausea, vomiting, diarrhea, hiccups, heartburn, dizziness, palpitations, hypertension, mouth problems.

Nicorette Clinical Trials

See Literature

Nicorette Note

Not Applicable

Nicorette Patient Counseling

See Literature