Nicorette Generic Name & Formulations
Nicotine polacrilex 2mg, 4mg; chewing gum; sugar-free; contains sodium, calcium; mint, fresh mint, white ice mint, cinnamon surge, fruit chill, or original flavor.
Gum—20, 100, 110, 200; Lozenge—(mint, cherry)—72; (original)—108; Mini lozenge—20, 81, 108, 135
Adjunct in smoking cessation therapy.
Nicorette Dosage and Administration
Start on quit day. Use 2mg if patient smoked first cigarette >30 mins after waking up; use 4mg if patient smoked first cigarette within 30 mins of waking up. Chew gum slowly until it tingles; park between cheek and gum; repeat until most of the tingle is gone (about 30 mins). ≥18yrs: Use 1 piece every 1–2hrs for 6 weeks (at least 9 pieces/day), then every 2–4hrs for 3 weeks, then every 4–8hrs for 3 weeks, then stop; max 24 pieces/day. If strong or frequent cravings, may use 2nd piece within the hour; avoid continuous use.
<18yrs: not recommended.
Nicorette Boxed Warnings
Cardiovascular disease, recent heart attack, irregular heart beat. Uncontrolled hypertension. Peptic ulcer disease. Diabetes. History of seizures. Sodium-restricted diet. Discontinue and evaluate if irregular heart beat, palpitations, mouth/teeth/jaw problems, persistent indigestion, severe sore throat, nicotine overdose symptoms, or allergic reactions occur. Keep out of reach of children and pets. Pregnancy. Nursing mothers.
Do not eat or drink for 15 mins before and during use. Concomitant other non-nicotine smoking cessation drug. Concomitant antidepressants or anti-asthmatic drugs; may need to adjust dose.
Nicorette Adverse Reactions
Nausea, vomiting, diarrhea, hiccups, heartburn, dizziness, palpitations, hypertension, mouth problems.
Nicorette Clinical Trials
Nicorette Patient Counseling