Nicorette Lozenge

  • Smoking

Nicorette Lozenge Generic Name & Formulations

General Description

Nicotine polacrilex 2mg, 4mg; contains sodium, phenylalanine; mint, cherry, or original flavor.

How Supplied

Gum—20, 100, 110, 200; Lozenge—(mint, cherry)—72; (original)—108; Mini lozenge—20, 81, 108, 135


Nicorette Lozenge Indications


Adjunct in smoking cessation therapy.

Nicorette Lozenge Dosage and Administration


Start on quit day. Do not chew or swallow lozenge. Use 2mg if patient smoked first cigarette >30 mins after waking up; use 4mg if patient smoked first cigarette within 30 mins of waking up. Dissolve slowly in mouth; minimize swallowing. ≥18yrs: 1 lozenge every 1–2hrs (at least 9 lozenges/day) for 6 weeks, then every 2–4hrs for 3 weeks, then every 4–8hrs for 3 weeks, then stop; max 5 lozenges/6hrs (20 lozenges/day).


<18yrs: not recommended.

Nicorette Lozenge Contraindications

Not Applicable

Nicorette Lozenge Boxed Warnings

Not Applicable

Nicorette Lozenge Warnings/Precautions


Cardiovascular disease, recent heart attack, irregular heart beat. Uncontrolled hypertension. Peptic ulcer disease. Diabetes. History of seizures. Sodium-restricted diet. Discontinue and evaluate if irregular heart beat, palpitations, mouth/teeth/jaw problems, persistent indigestion, severe sore throat, nicotine overdose symptoms, or allergic reactions occur. Keep out of reach of children and pets. Pregnancy. Nursing mothers.

Nicorette Lozenge Pharmacokinetics

See Literature

Nicorette Lozenge Interactions


Do not eat or drink for 15 mins before and during use. Concomitant other non-nicotine smoking cessation drug. Concomitant antidepressants or anti-asthmatic drugs; may need to adjust dose.

Nicorette Lozenge Adverse Reactions

Adverse Reactions

Nausea, vomiting, diarrhea, hiccups, heartburn, dizziness, palpitations, hypertension, mouth problems.

Nicorette Lozenge Clinical Trials

See Literature

Nicorette Lozenge Note

Not Applicable

Nicorette Lozenge Patient Counseling

See Literature