Indications for NARCAN NASAL SPRAY:
Reversal of known or suspected opioid overdose, including respiratory and/or CNS depression.
Adults and Children:
Give as single spray intranasally into one nostril. May give additional doses (using a new nasal spray) every 2–3 mins in alternate nostrils if unresponsive or relapses into respiratory depression. Seek immediate emergency medical assistance after the first dose.
Not a substitute for emergency medical care. Known or suspected opioid dependence; abrupt reversal may precipitate acute withdrawal syndrome. Monitor patients with satisfactory response due to long duration of some narcotics. Post-op use in pre-existing cardiac disease. Have other resuscitative measures available. Elderly. Pregnancy; monitor for neonatal withdrawal symptoms. Nursing mothers.
Caution with cardiotoxic drugs. Incomplete reversal of buprenorphine or pentazocine; may require higher naloxone dose.
Increased BP, musculoskeletal pain, headache, nasal effects (eg, dryness, edema, congestion, inflammation); opioid withdrawal.
Single-dose nasal spray—2