Naphazoline Hcl

  • Ocular allergy/inflammation

Naphazoline Hcl Generic Name & Formulations

General Description

Naphazoline HCl 1mg (0.1%); oph soln; contains benzalkonium chloride.

Pharmacological Class

Sympathomimetic (imidazoline derivative).

How Supplied



Naphazoline Hcl Indications


For use as a topical ocular vasoconstrictor.

Naphazoline Hcl Dosage and Administration

Adults and Children

Instill 1 or 2 drops in the conjunctival sac(s) every 3–4hrs as needed.

Naphazoline Hcl Contraindications


Anatomically narrow angle or in narrow-angle glaucoma.

Naphazoline Hcl Boxed Warnings

Not Applicable

Naphazoline Hcl Warnings/Precautions


Hypertension. Cardiovascular abnormalities. Diabetes. Hyperthyroidism. Infection. Injury. Children (esp. infants): may result in CNS depression leading to coma and marked reduction in body temperature. Discontinue if no relief obtained within 48hrs of therapy, if irritation, blurring or redness persists or increases, or if symptoms of systemic absorption occur. Pregnancy (Cat.C). Nursing mothers.

Naphazoline Hcl Pharmacokinetics

See Literature

Naphazoline Hcl Interactions


Concomitant maprotiline or tricyclic antidepressants may potentiate pressor effect. Severe hypertensive crisis possible with concomitant MAOIs.

Naphazoline Hcl Adverse Reactions

Adverse Reactions

Ocular (eg, mydriasis, increased redness, irritation, discomfort, blurring, punctate keratitis, lacrimation, increased intraocular pressure); systemic (eg, dizziness, headache, nausea, sweating, nervousness, drowsiness, weakness, hypertension, cardiac irregularities, hyperglycemia).

Naphazoline Hcl Clinical Trials

See Literature

Naphazoline Hcl Note

Not Applicable

Naphazoline Hcl Patient Counseling

See Literature