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Muse Generic Name & Formulations
Legal Class
Rx
General Description
Alprostadil 125mcg, 250mcg, 500mcg, 1000mcg; urethral suppository.
Pharmacological Class
Prostaglandin.
How Supplied
Urethral supps—6
Manufacturer
Muse Indications
Indications
Erectile dysfunction.
Muse Dosage and Administration
Adult
Supervise titration. Initially 125–250mcg inserted in urethra after urination; adjust dose in stepwise manner on separate occasions; max 2 supps/day.
Children
Not recommended.
Muse Contraindications
Contraindications
Urethral stricture. Balanitis. Severe hypospadias and curvature. Acute or chronic urethritis. Predisposition to venous thrombosis (eg, sickle cell anemia or trait). Hyperviscosity syndrome. Patients for whom sexual activity is inadvisable or contraindicated. If partner is pregnant, use condom; if partner is of childbearing age, use contraception.
Muse Boxed Warnings
Not Applicable
Muse Warnings/Precautions
Warnings/Precautions
Exclude reversible causes. Hypotension. Bleeding disorders. Priapism. Pregnancy (Cat.C): see Contraindications.
Muse Pharmacokinetics
See Literature
Muse Interactions
Interactions
Effect attenuated by drugs that interfere with erectile function (eg, decongestants). Caution with anticoagulants.
Muse Adverse Reactions
Adverse Reactions
Penile, urethral, or testicular pain, urethral burning, minor urethral bleeding/spotting, dizziness, hypotension, flu symptoms, rhinitis, others. Infrequent: priapism. Partners: vaginal burning/itching.
Muse Clinical Trials
See Literature
Muse Note
Not Applicable
Muse Patient Counseling
See Literature
