Monoket Generic Name & Formulations
Isosorbide mononitrate 10mg, 20mg; scored tabs.
Prophylaxis and treatment of angina. Not for acute attacks.
Monoket Dosage and Administration
20mg upon awakening then 20mg 7 hrs later. Small patients: may start with 5mg per dose for 1 day, then increase to 10mg by 2nd or 3rd day (scheduled as above).
Concomitant PDE-5 inhibitors (eg, sildenafil, tadalafil, vardenafil), riociguat.
Monoket Boxed Warnings
Acute MI. CHF. Hypotension. Volume depletion. Hypertrophic cardiomyopathy. Monitor for tolerance. Pregnancy (Cat.B). Nursing mothers.
See Contraindications. Severe hypotension, syncope, or myocardial ischemia with PDE-5 inhibitors; or hypotension with riociguat. Orthostatic hypotension with alcohol, other vasodilators, calcium channel blockers.
Monoket Adverse Reactions
Headache, dizziness, orthostatic hypotension, GI upset, upper respiratory infection.
Monoket Clinical Trials
Monoket Patient Counseling