Arthritis/rheumatic disorders:

Indications for MOBIC:

Osteoarthritis. Rheumatoid arthritis. Juvenile rheumatoid arthritis pauciarticular and polyarticular course.

Adult Dosage:

Use lowest effective dose for shortest duration. ≥18yrs: 7.5mg once daily; max 15mg once daily. Hemodialysis: max 7.5mg/day. Not interchangeable with other forms of oral meloxicam.

Children Dosage:

Use lowest effective dose for shortest duration. <2yrs or <60kg: not recommended. JRA: ≥2yrs or ≥60kg: 7.5mg once daily. Not interchangeable with other forms of oral meloxicam.

MOBIC Contraindications:

Aspirin allergy. Coronary artery bypass graft surgery.

Boxed Warning:

Risk of serious cardiovascular and gastrointestinal events.

MOBIC Warnings/Precautions:

Increased risk of serious cardiovascular events (including MI, stroke). Avoid in recent MI, severe heart failure; if necessary, monitor. Increased risk of serious GI adverse events (including inflammation, bleeding, ulceration, perforation). History of ulcer disease and/or GI bleeding. Hypertension; monitor BP closely. Hepatic or renal impairment. Discontinue if signs/symptoms of liver disease develop, or if abnormal LFTs persist or worsen. Dehydration. Hypovolemia. Advanced renal disease: not recommended. Hyperkalemia. Coagulation disorders. Monitor CBCs, blood chemistry, hepatic, and renal function in long-term therapy. Pre-existing asthma. May mask signs of infection or fever. Discontinue at 1st sign of rash or any other hypersensitivity. Elderly. Debilitated. Labor & delivery. May be associated with a reversible delay in ovulation in females of reproductive potential. Pregnancy (avoid during ≥30 weeks gestation): increased risk of premature closure of the fetal ductus arteriosus; (20–30 weeks gestation): may cause fetal renal dysfunction/oligohydramnios; if treatment needed, limit dose and duration of use. Nursing mothers.

MOBIC Classification:

NSAID (oxicam).

MOBIC Interactions:

Avoid concomitant aspirin, salicylates (eg, diflunisal, salsalate) or other NSAIDs. Increased risk of GI bleed with anticoagulants, antiplatelets, oral corticosteroids, SSRIs, SNRIs, smoking, alcohol, or prolonged NSAID therapy; monitor. May antagonize, or increase risk of renal failure with diuretics (eg, loop or thiazides), ACE inhibitors, ARBs, or β-blockers; monitor closely. May potentiate lithium, methotrexate, cyclosporine; monitor for toxicity. Concomitant with pemetrexed may increase risk of pemetrexed-associated myelosuppression, renal, and GI toxicity.

Adverse Reactions:

Diarrhea, upper RTI, dyspepsia, influenza-like symptoms; cardiovascular thrombotic events, GI ulcer/bleed, hepatotoxicity, renal toxicity, edema, hypersensitivity reactions, serious skin reactions (eg, Stevens-Johnson Syndrome, toxic epidermal necrolysis), Drug Reaction with Eosinophilia and Systemic Symptoms (discontinue if occurs), anemia.

Generic Drug Availability:

YES

How Supplied:

Tabs—100

Pricing for MOBIC

15mg tablet (Qty: 30)
Appx. price $6
GoodRx