Select therapeutic use:

Contraception:

Indications for MIRENA:

Intrauterine contraception for up to 6yrs.

Adult:

See full labeling. Insert into uterine cavity as directed. Reexamine 4–6wks after insertion and once a year thereafter, or as clinically indicated. Replace after 6yrs.

Children:

Pre-menarche: not indicated.

Contraindications:

Congenital or acquired uterine anomaly. Acute or history of pelvic inflammatory disease (PID) unless subsequent intrauterine pregnancy occurred. Postpartum endometritis or septic abortion in past 3months. Uterine or cervical neoplasia. Breast or other progestin-sensitive cancer. Uterine bleeding of unknown cause. Untreated acute cervicitis or vaginitis. Acute liver disease or liver tumor. Conditions associated with increased susceptibility to pelvic infections. Retained IUD. Pregnancy.

Warnings/Precautions:

History or risk of ectopic pregnancy. Assure suitable uterine anatomy before inserting. Risk of spontaneous abortion, miscarriage, sepsis, premature labor or delivery, congenital anomalies: remove if pregnant. Consider risks of PID before using. Exclude endometrial pathology if bleeding irregularities develop with prolonged treatment. Risk of perforation, expulsion and ovarian cysts. Increased risk of perforation in lactating women or if inserted in women with fixed retroverted uteri or during postpartum period; delay insertion a minimum ≥6wks or until involution is complete after delivery or a second trimester abortion. Remove device if any of these occur: PID, endometritis, genital actinomycosis, perforation, any sign of expulsion. Consider removal if coagulopathy, migraine, transient cerebral ischemia, severe headache, marked increase in BP, severe arterial disease (eg, stroke, MI), jaundice or uterine/cervical malignancy occurs. Nursing mothers.

Pharmacologic Class:

Progestin IUD.

Interactions:

May be antagonized by CYP3A4 inducers. May be potentiated by CYP3A4 inhibitors. Caution with anticoagulants.

Adverse Reactions:

Menstrual bleeding pattern changes, abdominal or pelvic pain, amenorrhea, headache, migraine, genital discharge, vulvovaginitis; ectopic or intrauterine pregnancy, PID, perforation, ovarian cysts, sepsis (during insertion).

How Supplied:

System—1

Pricing for MIRENA

52mg iud (Qty: 1)
Appx. price $1125
GoodRx

Menorrhagia:

Indications for MIRENA:

Treatment of heavy menstrual bleeding for up to 5yrs in women who choose to use intrauterine contraception as their method of contraception.

Adult:

See full labeling. Insert into uterine cavity as directed. Reexamine 4–6wks after insertion and once a year thereafter, or as clinically indicated. Replace after 5yrs if continued use is needed (limited data beyond 5yrs).

Children:

Pre-menarche: not indicated.

Contraindications:

Congenital or acquired uterine anomaly. Acute or history of pelvic inflammatory disease (PID) unless subsequent intrauterine pregnancy occurred. Postpartum endometritis or septic abortion in past 3months. Uterine or cervical neoplasia. Breast or other progestin-sensitive cancer. Uterine bleeding of unknown cause. Untreated acute cervicitis or vaginitis. Acute liver disease or liver tumor. Conditions associated with increased susceptibility to pelvic infections. Retained IUD. Pregnancy.

Warnings/Precautions:

History or risk of ectopic pregnancy. Assure suitable uterine anatomy before inserting. Risk of spontaneous abortion, miscarriage, sepsis, premature labor or delivery, congenital anomalies: remove if pregnant. Consider risks of PID before using. Exclude endometrial pathology if bleeding irregularities develop with prolonged treatment. Risk of perforation, expulsion and ovarian cysts. Increased risk of perforation in lactating women or if inserted in women with fixed retroverted uteri or during postpartum period; delay insertion a minimum ≥6wks or until involution is complete after delivery or a second trimester abortion. Remove device if any of these occur: PID, endometritis, genital actinomycosis, perforation, any sign of expulsion. Consider removal if coagulopathy, migraine, transient cerebral ischemia, severe headache, marked increase in BP, severe arterial disease (eg, stroke, MI), jaundice or uterine/cervical malignancy occurs. Nursing mothers.

Pharmacologic Class:

Progestin IUD.

Interactions:

May be antagonized by CYP3A4 inducers. May be potentiated by CYP3A4 inhibitors. Caution with anticoagulants.

Adverse Reactions:

Menstrual bleeding pattern changes, abdominal or pelvic pain, amenorrhea, headache, migraine, genital discharge, vulvovaginitis; ectopic or intrauterine pregnancy, PID, perforation, ovarian cysts, sepsis (during insertion).

How Supplied:

System—1

Pricing for MIRENA

52mg iud (Qty: 1)
Appx. price $1125
GoodRx