• Miscellaneous ocular agents

Miostat Generic Name & Formulations

General Description

Carbachol 0.01%; per mL; soln for intraocular inj.

Pharmacological Class


How Supplied

Single-use vial (1.5mL)—12

Miostat Indications


To obtain miosis during eye surgery. To reduce the intensity of intraocular pressure elevation in the first 24 hours after cataract surgery.

Miostat Dosage and Administration


See full labeling. Withdraw contents into a dry sterile syringe and replace the needle with an atraumatic cannula prior to intraocular instillation. Gently instill no more than ½ mL into the anterior chamber; may be instilled before or after securing sutures. Usually within 2–5 mins after application for maximal miosis effects.


Not established.

Miostat Contraindications

Not Applicable

Miostat Boxed Warnings

Not Applicable

Miostat Warnings/Precautions


For single-dose intraocular use only. Acute cardiac failure. Bronchial asthma. Peptic ulcer. Hyperthyroidism. GI spasm. Urinary tract obstruction. Parkinson's disease. Latex allergy. Pregnancy (Cat.C). Nursing mothers.

Miostat Pharmacokinetics

See Literature

Miostat Interactions

Miostat Adverse Reactions

Adverse Reactions

Corneal clouding, persistent bullous keratopathy, retinal detachment, postoperative iritis; flushing, sweating, epigastric distress, abdominal cramps, tightness in urinary bladder, headache.

Miostat Clinical Trials

See Literature

Miostat Note

Not Applicable

Miostat Patient Counseling

See Literature