Midol Complete

  • Dysmenorrhea

Midol Complete Generic Name & Formulations

General Description

Acetaminophen 500mg, caffeine 60mg, pyrilamine maleate 15mg; caplets.

Pharmacological Class

Analgesic + diuretic + sedating antihistamine.

See Also

How Supplied

Caplets, Complete—24

Midol Complete Indications



Midol Complete Dosage and Administration


2 caplets every 6hrs; max 6/day.


<12yrs: consult physician.

Midol Complete Contraindications


Concomitant other acetaminophen-containing products.

Midol Complete Boxed Warnings

Not Applicable

Midol Complete Warnings/Precautions


Acetaminophen: hepatic disease. Pyrilamine: asthma, emphysema, other lower respiratory disorders. Glaucoma. GI or urinary obstruction. Discontinue if skin or allergic reactions occur. Reevaluate if pain worsens or lasts >10 days or fever persists or worsens >3 days. Pregnancy. Nursing mothers.

Midol Complete Pharmacokinetics

See Literature

Midol Complete Interactions


Acetaminophen: increased risk of hepatotoxicity if overdosage or ≥3 alcoholic drinks/day. Pyrilamine: potentiates CNS depression with alcohol, other CNS depressants. Caution with warfarin, sedatives, or tranquilizers.

Midol Complete Adverse Reactions

Adverse Reactions

Acetaminophen: hepatotoxicity (overdosage). Pyrilamine: drowsiness, dizziness, paradoxical excitation (esp. in children). Caffeine: nervousness, irritability, sleeplessness, occasional palpitations.

Midol Complete Clinical Trials

See Literature

Midol Complete Note

Not Applicable

Midol Complete Patient Counseling

See Literature