Hyperacidity, GERD, and ulcers:
Indications for: METOZOLV ODT
Short-term (4–12 weeks) therapy for symptomatic refractory GERD.
Adult Dosage:
Allow tablet to dissolve on tongue. 10–15mg 4 times daily 30mins before meals and at bedtime. Intermittent symptoms: up to 20mg prior to provoking situation; max 12 weeks per therapeutic course. Renal impairment: reduce dose.
Children Dosage:
Not established.
METOZOLV ODT Contraindications:
When stimulation of GI motility may be dangerous (eg, obstruction, perforation, or hemorrhage). Pheochromocytoma. Epilepsy. Concomitant drugs which may cause extrapyramidal reactions (eg, antidepressants, antipsychotics, neuroleptics).
METOZOLV ODT Warnings/Precautions:
Discontinue if signs/symptoms of tardive dyskinesia develop; risk increases with duration of treatment and total cumulative dose. Parkinsonism. History of depression. Hypertension. CHF. Arrhythmia. Elderly. Pregnancy (Cat.B). Nursing mothers.
METOZOLV ODT Classification:
Prokinetic.
METOZOLV ODT Interactions:
Hypertensive crisis with MAOIs. Additive sedation with alcohol, other CNS depressants. Antagonized by anticholinergics and narcotics. Monitor insulin use; may diminish gastric and accelerate intestinal absorption of drugs or food.
Adverse Reactions:
Headache, nausea, vomiting, fatigue, somnolence, dizziness, extrapyramidal effects, parkinsonism, tardive dyskinesia, neuroleptic malignant syndrome, hypertension.
How Supplied:
Tabs—10 x 10 (blister packs)
Nausea:
Indications for: METOZOLV ODT
To relieve symptoms associated with acute and recurrent diabetic gastroparesis.
Adult Dosage:
Allow tablet to dissolve on tongue. 10mg 4 times daily 30mins before meals and at bedtime for 2–8 weeks. Renal impairment: reduce dose.
Children Dosage:
Not established.
METOZOLV ODT Contraindications:
When stimulation of GI motility may be dangerous (eg, obstruction, perforation, or hemorrhage). Pheochromocytoma. Epilepsy. Concomitant drugs which may cause extrapyramidal reactions (eg, antidepressants, antipsychotics, neuroleptics).
METOZOLV ODT Warnings/Precautions:
Discontinue if signs/symptoms of tardive dyskinesia develop; risk increases with duration of treatment and total cumulative dose. Parkinsonism. History of depression. Hypertension. CHF. Arrhythmia. Elderly. Pregnancy (Cat.B). Nursing mothers.
METOZOLV ODT Classification:
Antidopaminergic.
METOZOLV ODT Interactions:
Hypertensive crisis with MAOIs. Additive sedation with alcohol, other CNS depressants. Antagonized by anticholinergics and narcotics. Monitor insulin use; may diminish gastric and accelerate intestinal absorption of drugs or food.
Adverse Reactions:
Headache, nausea, vomiting, fatigue, somnolence, dizziness, extrapyramidal effects, parkinsonism, tardive dyskinesia, neuroleptic malignant syndrome, hypertension.
How Supplied:
Tabs—10 x 10 (blister packs)
