Indications for Megestrol Oral Suspension:
Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.
Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Monitor for signs/symptoms of adrenal insufficiency; consider empiric therapy if occurs. Diabetes. Renal impairment. Elderly. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.
May increase insulin requirements. Decreases indinavir levels.
GI upset, impotence, flatulence, rash, hypertension, fever, decreased libido, breakthrough bleeding, hyperglycemia, insomnia.