Meclizine Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Mechanism of Action
Meclizine Indications
Indications
Meclizine Dosage and Administration
Adult
Children
Renal Impairment
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Use caution in patients with renal impairment because the elderly population may have a decline in renal function with age.
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The pharmacokinetics of meclizine has not been evaluated in patients with renal impairment.
Hepatic Impairment
-
Use caution in patients with hepatic impairment.
-
Hepatic impairment may result in increased systemic exposure of meclizine.
-
The pharmacokinetics of meclizine has not been evaluated in patients with hepatic impairment.
Other Modifications
Genetic CYP2D6 Polymorphism
-
Monitor for adverse reactions and clinical effect in patients with CYP2D6 polymorphism.
Meclizine Contraindications
Not Applicable
Meclizine Boxed Warnings
Not Applicable
Meclizine Warnings/Precautions
Warnings/Precautions
Meclizine Pharmacokinetics
Absorption
Maximum plasma concentrations reached at a median Tmax value of 3 hours post-dose (range: 1.5 to 6 hours).
Elimination
Meclizine Interactions
Interactions
Meclizine Adverse Reactions
Adverse Reactions
Meclizine Clinical Trials
See Literature